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NCT07312344Recruiting

Impact of Exercise-derived Extracellular Vesicle in Blood and Physical Fitness Data in Overweight/Obesity Individuals

Exploring the Impact of Exercise-derived Extracellular Vesicle in Blood and Physical Fitness Data in Overweight/Obesity Individuals on Lymphangiogenesis

Source: ClinicalTrials.gov · Last updated 31 Dec 2025

Brief summary (registry, in English)

This project aims to study the effect of exercise in the obesity/overweight on the changes of physical fitness and blood components. This will provide novel knowledge for medical staffs, researchers, or companies developing alternative strategies for treating obesity/overweight, including drug development and health promotion project to delay or prevent the onset of the disease.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
20 (estimated)
First submitted
30 Nov 2025
Start date
30 Aug 2025
Primary completion date
31 Jan 2026
Lead sponsor
Mahidol University
Diseases
Obesity
NCT number
NCT07312344

What you commit to

  • Study type: Interventional
  • Planned participants: 20
  • From 30 Aug 2025 to the primary completion date, 31 Jan 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • History of previous lower limb surgery, such as hip, knee, or ankle replacement

Other illness

  • History of respiratory diseases, such as asthma, emphysema, or chronic obstructive pulmonary disease
  • History of cardiovascular diseases, such as coronary heart disease, aortic disease, arrhythmia, or deep vein thrombosis
  • History of high blood pressure (hypertension)
  • History of vestibular system diseases, such as Meniere's disease or otitis media
  • History of neurological disease, such as severe Parkinson's disease or stroke
  • History of musculoskeletal diseases, such as severe osteoarthritis
  • History of severe brain disease, such as dementia
  • Severe visual or hearing impairment
  • Have a cognitive and comprehensive impairment and unable to complete the intervention

Other

  • Smoking, substance abuse, or alcohol addiction
  • Have high physical activity or regularly exercise

Who the study is looking for

  • Male or female individuals aged between 25-45 years
  • Thai nationality
  • Ability to walk or perform daily activities independently, without the use of an assistive device
  • Body mass index (BMI) between 25-35 kg/m²
  • Low physical activity levels or sedentary lifestyle based on the World Health Organization 2020
    • The levels of moderate-intensity physical activity \< 150-300 minutes per week or the levels of vigorous-intensity physical activity \< 75-150 minutes per week
    • Moderate-intensity physical activity: fast walking and bicycling. Vigorous-intensity physical activity: running, aerobic dance, and swimming All participants are required to meet all inclusion criteria to be eligible for the research project.

Age in the registry: 25 years to 45 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Chakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital
Coordinator of this site? Confirm its status
Mueang Samut PrakanThailandRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.