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NCT07312409Recruiting

Does Taurine Supplementation Improve Vascular Function and Orthostatic Responses in Long COVID?

Source: ClinicalTrials.gov · Last updated 5 Jun 2026

Brief summary (registry, in English)

Millions have developed Long COVID (LC), and recent findings show an association between taurine deficiency (an amino acid) and symptoms in LC. Cost-effective and accessible interventions are needed to improve welfare and reduce healthcare costs. We will investigate the efficacy of 12-weeks of taurine supplementation (self-administered), on vascular function and the cardio/cerebrovascular responses to upright posture. We will measure resting vascular function with an EndoPAT device, resting heart rate variability, and the blood pressure, heart rate, and brain blood flow responses to 5 minutes of head-up tilt before and after weeks of taurine supplementation in LC. We hypothesize that the 12 weeks of supplementation will improve both resting vascular function and the responses to upright tilt. In turn, we hypothesize that symptoms will also improve (as measured by questionnaires).

Status (registry)
Recruiting
Study type
Observational
Enrollment
30 (estimated)
First submitted
17 Dec 2025
Start date
1 Jun 2026
Primary completion date
30 Jun 2027
Lead sponsor
York University
NCT number
NCT07312409

What you commit to

  • Study type: Observational
  • Planned participants: 30
  • From 1 Jun 2026 to the primary completion date, 30 Jun 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Blood clotting disorders

Other

  • Inability to undergo tilt table testing for 5 minutes
  • Inability to transport selves to York University from their homes
  • Inability to speak English, or provide a translator

Who the study is looking for

  • Participants will have had symptoms of Long COVID post-infection for at least 3 months

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
York University
Coordinator of this site? Confirm its status
TorontoCanadaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.