NCT07312734Recruiting
Study to Enable New Diagnostics for Pulmonary Microbes in People With CF
Study to Enable New Diagnostics for Pulmonary Microbes in People With CF (SEND-CF)
Source: ClinicalTrials.gov · Last updated 2 Jul 2026
Brief summary (registry, in English)
Sputum culture has been the best approach to detect harmful bacteria in the lungs of people with cystic fibrosis (CF). With the widespread use of new CF therapies (like Trikafta and Alyftrak), it is more difficult for people with CF to produce sputum even though they still have harmful bacteria in their lungs. The SEND-CF study is being done to see if there are other ways to detect harmful bacteria in the lungs.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 23 Oct 2025
- Start date
- 30 Mar 2026
- Primary completion date
- 1 Aug 2027
- Lead sponsor
- Chris Goss
- Diseases
- Cystic fibrosis
- NCT number
- NCT07312734
What you commit to
- Study type: Observational
- Planned participants: 300
- From 30 Mar 2026 to the primary completion date, 1 Aug 2027
- 9 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of active malignancy (or treatment for malignancy) in 12 months prior to the study visit
Other illness
- History of solid organ transplantation
Other
- Pregnant
Who the study is looking for
- ≥ 16 years of age on day of study visit
- Documentation of CF Diagnosis
- Able to expectorate sputum
- Percent predicted FEV1 ≥ 30%
Age in the registry: 16 years to - · Sex: All · Does not accept healthy volunteers
Sites (9)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nationwide Children's Hospital Coordinator of this site? Confirm its status | Columbus | United States | Not yet recruiting |
| University of Texas, Southwestern Coordinator of this site? Confirm its status | Dallas | United States | Recruiting |
| University of California San Diego Coordinator of this site? Confirm its status | La Jolla | United States | Not yet recruiting |
| Froedtert & Medical College of Wisconsin Coordinator of this site? Confirm its status | Milwaukee | United States | Recruiting |
| The Minnesota Cystic Fibrosis Center Coordinator of this site? Confirm its status | Minneapolis | United States | Recruiting |
| University of Nebraska Medical Center Coordinator of this site? Confirm its status | Omaha | United States | Not yet recruiting |
| University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
| University of Pittsburgh Medical Center Coordinator of this site? Confirm its status | Pittsburgh | United States | Recruiting |
| Washington University School of Medicine Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.