NCT07313462Recruiting
Escalation vs. Induction Therapy Strategy in Patients With Early-Onset MS After Age 50
Source: ClinicalTrials.gov · Last updated 2 Jan 2026
Brief summary (registry, in English)
The objective of this study is to evaluate the risk of inflammatory disease activity by retrospectively comparing two therapeutic strategies (escalation group and induction group). The investigators also aim to identify factors associated with inflammatory relapse and treatment-related complications.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 830 (estimated)
- First submitted
- 17 Dec 2025
- Start date
- 7 Feb 2025
- Primary completion date
- 28 Feb 2026
- Lead sponsor
- University Hospital, Strasbourg, France
- Diseases
- Multiple sclerosis
- NCT number
- NCT07313462
What you commit to
- Study type: Observational
- Planned participants: 830
- From 7 Feb 2025 to the primary completion date, 28 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \- Patients with early progressive MS
Who the study is looking for
- Patients with RRMS onset after age 50
- Patients who started their first disease-modifying therapy within 2 years of the first symptoms
- Patients Treated with moderately effective disease-modifying antirheumatic drugs (DMARDs) (teriflunomide, dimethyl fumarate or diroximel fumarate, glatiramer acetate, interferon beta, peginterferon)
- Patient treated with highly effective DMARDs (fingolimod, ponesimod, natalizumab, rituximab, ocrelizumab, ofatumumab, cladribine)
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre d'Investigation Clinique - CHU de Strasbourg - France Coordinator of this site? Confirm its status | Strasbourg | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.