NCT07314177Completed
Effects of Three Dietary Strategies on Body Composition and Metabolic Health in Adults With Overweight or Obesity
Comparative Effects of Three Dietary Strategies on Body Composition, Metabolic Markers, and Metabolic Syndrome in Adults With Overweight/Obesity: A Randomized Pilot Trial
Source: ClinicalTrials.gov · Last updated 2 Jan 2026
Brief summary (registry, in English)
This study aims to compare the effects of three dietary interventions-a traditional Mediterranean diet, a Mediterranean low-carbohydrate diet, and a high-protein diet-on body composition, metabolic health markers, and metabolic syndrome remission in adults with overweight or obesity. A total of 45 participants will be randomly assigned to one of the three diets for 12 weeks, with regular follow-up by dietitians. Measurements will include weight, body fat, muscle mass, waist and hip circumference, blood pressure, and blood tests to assess glucose, cholesterol, inflammation, and other metabolic parameters. The findings will help determine whether one dietary pattern is more effective than others in improving short-term health outcomes in this population.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 45 (actual)
- First submitted
- 28 Aug 2025
- Start date
- 8 Sept 2024
- Primary completion date
- 20 Apr 2025
- Lead sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
- Diseases
- Obesity
- NCT number
- NCT07314177
What you commit to
- Study type: Interventional
- Participants enrolled: 45
- From 8 Sept 2024 to the primary completion date, 20 Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of medications known to affect body weight, metabolism, or appetite (e.g., glucocorticoids, weight-loss drugs, antipsychotics)
Other illness
- Diagnosis of type 1 diabetes, cardiovascular disease, cancer, chronic kidney disease, liver disease, or other serious chronic conditions that could interfere with the intervention
- History of bariatric surgery or weight-loss program within the past 6 months
- Any food allergy or intolerance that would preclude adherence to the assigned diet
- Any condition or circumstance that, in the opinion of the investigators, would make the participant unsuitable for the study
Other
- Pregnancy or breastfeeding
- Current participation in another clinical trial
- Alcohol or substance abuse
Who the study is looking for
- Adults aged 20-70 years
- Body mass index (BMI) ≥ 25 kg/m² (overweight or obesity)
- Stable body weight (± 2 kg) in the last 3 months prior to screening
- Willingness to follow one of the prescribed dietary interventions for 12 weeks
- Ability to attend scheduled follow-up visits and complete study assessments
- Provided written informed consent prior to study participation
Age in the registry: 20 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Edificio SAI Coordinator of this site? Confirm its status | Zaragoza | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.