NCT07320222Not yet recruitingPhase 1
CARE-Melanoma Trial
A Coordinated Approach to Peri-operative Rehabilitation to Enhance Outcomes in Melanoma: the CARE-Melanoma Pilot Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 6 Jan 2026
Brief summary (registry, in English)
Melanoma, a serious skin cancer, is increasingly prevalent in Canada. Surgical intervention is essential but poses significant physical and emotional challenges. Rehabilitation is crucial for recovery, helping patients regain strength and confidence while addressing psychological needs. In Ontario, new neoadjuvant chemotherapy regimens are being introduced to improve outcomes by shrinking tumors before surgery. Despite advancements, pre-habilitation and early post-operative rehabilitation services for melanoma patients are currently lacking. This pilot trial aims to evaluate the feasibility and effectiveness of pre- and post-surgery rehabilitation strategies for melanoma patients. The purpose of this pilot trial is to determine the feasibility and preliminary effectiveness of a rehabilitation strategy for individuals with melanoma pre- and post-surgery.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 24 Nov 2025
- Start date
- 20 Jan 2026
- Primary completion date
- 30 Nov 2026
- Lead sponsor
- McMaster University
- Diseases
- Melanoma
- NCT number
- NCT07320222
What you commit to
- Study type: Interventional · Phase 1
- Planned participants: 30
- From 20 Jan 2026 to the primary completion date, 30 Nov 2026
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- are not undergoing neo-adjuvant chemotherapy
Other illness
- self-report any chronic condition, cognitive impairment, or injury that would prevent them from participating independently in moderate intensity exercise
Age
- \<18 years of age
Who the study is looking for
- melanoma diagnosis
- English speaking,
- adults (\>18 years of age)
- scheduled to receive surgery after a neoadjuvant chemotherapy regime
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.