NCT07320261Not yet recruiting
Cardiac CT Evaluation of EAT in AF vs. Non-AF Subjects
Cardiac Computed Tomography Evaluation of Epicardial Adipose Tissue Differences Between Patients With Atrial Fibrillation and Non-Atrial Fibrillation Individuals
Source: ClinicalTrials.gov · Last updated 6 Jan 2026
Brief summary (registry, in English)
The goal of this cross-sectional study is to explore the relationship between atrial structural characteristics (such as epicardial adipose tissue infiltration and atrial size) and atrial fibrillation (AF), as well as the differences in these characteristics among different AF subtypes. It will also clarify the independent association between pericardial fat distribution and AF (and its subtypes) after excluding confounding factors. The main questions it aims to answer are: * What are the differences in epicardial adipose tissue volume and atrial size among patients with sinus rhythm, paroxysmal AF, and persistent AF? * Is pericardial fat distribution independently associated with AF and its subtypes after adjusting for confounding factors such as age, hypertension, and left atrial enlargement? Researchers will enroll patients who undergo coronary CTA or left atrial CTA at The Second Affiliated Hospital of Zhejiang University School of Medicine, and match and divide them into three groups (sinus rhythm group, paroxysmal AF group, and persistent AF group) based on BMI and other factors. They will compare the differences in pericardial fat distribution and baseline characteristics among the three groups and analyze the independent association between pericardial fat and AF. Participants will: * Provide relevant clinical baseline data and CTA examination results * Complete the collection of demographic information, medical history, and laboratory test data The study duration is 6 months, starting from the date of ethical approval, with an expected end date of June 2026. A total of 600-900 participants (200-300 per group) will be enrolled to ensure the reliability and clinical applicability of the research conclusions.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 600 (estimated)
- First submitted
- 22 Dec 2025
- Start date
- 1 Jan 2026
- Primary completion date
- 28 Feb 2026
- Lead sponsor
- xiaoya wang
- Diseases
- Atrial fibrillation
- NCT number
- NCT07320261
What you commit to
- Study type: Observational
- Planned participants: 600
- From 1 Jan 2026 to the primary completion date, 28 Feb 2026
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Aged less than 18 years
Other
- Patients with incomplete clinical baseline data or unreadable CTA images;
- Patients who refuse to participate in the study or cannot cooperate with data collection;
- Other situations judged by the researchers to be unsuitable for inclusion in the study.
Who the study is looking for
- Patients who undergo coronary CTA or left atrial CTA examination at The Second Affiliated Hospital of Zhejiang University School of Medicine;
- Aged 18 years or older
- Cardiac rhythm status is confirmed as sinus rhythm, paroxysmal atrial fibrillation, or persistent atrial fibrillation;
- Willing to provide clinical baseline data and allow access to CTA examination results;
- Able to understand and cooperate with the data collection process of the study.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.