NCT07321275Completed
Ultra-early Chest CT for SAP Prediction
Ultra-early Chest CT Improves Risk Prediction of Stroke-associated Pneumonia: Model Development and External Validation in a Multicentre Retrospective Study
Source: ClinicalTrials.gov · Last updated 10 Mar 2026
Brief summary (registry, in English)
Stroke-associated pneumonia (SAP) is a common and serious complication after acute ischaemic stroke (AIS). Existing scores rely mainly on clinical variables, and the added prognostic value of inflammatory markers and early chest CT findings remains uncertain. We developed and externally validated an early multimodal model combining clinical severity, inflammation, and chest CT abnormalities, and explored risk-stratified associations between prophylactic antibiotics and SAP.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 1499 (actual)
- First submitted
- 19 Dec 2025
- Start date
- 15 Jan 2026
- Primary completion date
- 19 Feb 2026
- Lead sponsor
- Capital Medical University
- Diseases
- Stroke
- NCT number
- NCT07321275
What you commit to
- Study type: Observational
- Participants enrolled: 1499
- From 15 Jan 2026 to the primary completion date, 19 Feb 2026
- 8 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Insufficient clinical documentation to ascertain stroke-associated pneumonia occurrence within 7 days after stroke onset
Other
- Pneumonia;
- Chest CT images unavailable or incomplete for assessment;
Who the study is looking for
- patients aged ≥18 years;
- Admitted to a participating stroke centre with neuroimaging-confirmed acute ischaemic stroke ;
- Had chest CT performed within 24 hours of stroke onset.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rongcheng County People's Hospital Coordinator of this site? Confirm its status | Baoding | China | Unknown status |
| Xuanwu Hospita Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
| Ningjin County People's Hospital Coordinator of this site? Confirm its status | Fenghuang | China | Unknown status |
| Shihezi People's Hospital Coordinator of this site? Confirm its status | Shihezi | China | Unknown status |
| The Second Hospital of Hebei Medical University Coordinator of this site? Confirm its status | Shijiazhuang | China | Unknown status |
| First Affiliated Hospital of Soochow University Coordinator of this site? Confirm its status | Suzhou | China | Unknown status |
| Suzhou Municipal Hospital of Anhui Province Coordinator of this site? Confirm its status | Suzhou | China | Unknown status |
| Central Hospital of Xiangtan Coordinator of this site? Confirm its status | Xiangtan | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.