NCT07321353Recruiting
Survivors Journey+
Online Problem-Solving Intervention for Brain Tumor Survivors: A Two-site, Two-arm Pilot Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 7 Jan 2026
Brief summary (registry, in English)
The main goal of this pilot randomized controlled trial is to learn if an online program called "Survivors Journey" (SJ+) can help teens and young adults, ages 15-25, who are Pediatric Brain Tumor Survivors (PBTS), and their caregivers, manage everyday challenges better by using skills like problem-solving and coping skills. The main questions it aims to answer are: * Is the SJ+ program rated as feasible (\>50% enrollment rate and \>75% retention rate) and acceptable (\>80% satisfaction rate) by PBTS and their caregivers? * Does the SJ+ program have better outcomes in improving PBTS and caregiver wellbeing in comparison to an internet resource comparison (IRB) made for PBTS and their families? Participants will be randomized into two groups: one group will be given access to the online SJ+ program and receive weekly online coaching sessions, and the other group will be given access to an IRC. Outcomes will be assessed at baseline, treatment completion (\~ 3 months post-baseline), and at follow-up six months post-baseline. These outcomes include quality of life, internalizing symptoms, performance-based executive function skills, depression, and family impact.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 72 (estimated)
- First submitted
- 22 Dec 2025
- Start date
- 1 Aug 2025
- Primary completion date
- Sept 2027
- Lead sponsor
- Children's Hospital Medical Center, Cincinnati
- Diseases
- Childhood cancers
- NCT number
- NCT07321353
What you commit to
- Study type: Interventional
- Planned participants: 72
- From 1 Aug 2025 to the primary completion date, Sept 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- treatment \< 12 months ago and/or treatment did not include surgery, radiation, or chemotherapy
Other illness
- history of tuberous sclerosis or neurofibromatosis
- history of psychiatric hospitalization
- history of autism, reactive attachment disorder, psychosis, or other psychiatric diagnoses/conditions associated with significant risk of harm to self or others per caregiver
Other
- resides outside of the family home
- English is not the primary language spoken in the home
Who the study is looking for
- a diagnosis of a pediatric intracranial tumor
- tumor-directed treatment completed \> 12 months ago (treatment included: surgery, radiation, or chemotherapy)
- lives with parent/guardian(s)
- language: English must be the primary spoken language in the home
Age in the registry: 15 years to 25 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cincinnati Children's Hospital Medical Center Coordinator of this site? Confirm its status | Cincinnati | United States | Recruiting |
| Nationwide Children's Hospital Coordinator of this site? Confirm its status | Columbus | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.