NCT07321925Recruiting
Thermoacoustic Method for Estimating Liver Fat Fraction
Thermoacoustic Method for Estimating Liver Fat Fraction - Pilot Study I
Source: ClinicalTrials.gov · Last updated 7 Jan 2026
Brief summary (registry, in English)
The goal of this study is to use our Thermoacoustic Enhanced Ultrasound device to measure the fat levels in your liver and compare it to the the gold standard MRI PDFF measurements. Participants will have a scan with our device, then they will go have an abdominal MRI completed. The goal is to create a more accessible device to measure liver fat as it is an indicator for overall health and metabolic diseases.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 49 (estimated)
- First submitted
- 11 Dec 2025
- Start date
- 15 Aug 2025
- Primary completion date
- 30 Oct 2025
- Lead sponsor
- Endra Lifesciences
- Diseases
- Fatty liver disease (MASLD/MASH)
- NCT number
- NCT07321925
What you commit to
- Study type: Observational
- Planned participants: 49
- From 15 Aug 2025 to the primary completion date, 30 Oct 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Metal or electronic implants, including, but not limited to: pacemakers, metal clips, drug delivery pumps, hip implants, and neural stimulation devices, contraindicates for MRI.
Other illness
- Liver diseases other than MASLD/MASH/fibrosis including, but not limited to:
Other
- Known pregnancy the day of consent or becoming pregnant during study participation based on start date of last menstrual period).
- Cirrhosis
- Hepatocellular carcinoma
- Ascites
- Patients with broken, or injured skin, in the right upper abdominal quadrant.
- Body habitus, or anatomical variation, where the liver capsule is not accessible with ultrasound through the patient's right intercostal imaging window used in conventional ultrasound liver imaging.
- BMI greater than 50 kg/m2
- Patients with subcutaneous fat at measurement location less than or equal to 6mm.
- Patients with a missing liver lobe.
- Patients with peri-hepatic fat in the measurement location.
- Patients with focal liver lesions or anatomical structures in the measurement location, as detected by ultrasound.
Who the study is looking for
- Study participants are 18 or older.
- Able to understand, read, and provide written informed consent in English.
- Able to tolerate both ultrasound and MRI examinations.
- Able to lie flat, or on their side, for 20 minutes and pause breathing for up to 10 seconds.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| ENDRA Life Sciences Coordinator of this site? Confirm its status | Ann Arbor | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.