NCT07325019Completed
THE EFFECTS OF AEROBİC EXERCİSE ON NEUROVASCULAR UNİT AND CLİNİCAL PROGRESSİON MARKERS İN INDİVİDUALS WİTH MULTİPLE SCLEROSİS
Source: ClinicalTrials.gov · Last updated 8 Jan 2026
Brief summary (registry, in English)
This study is a randomised controlled trial designed to thoroughly investigate the effects of aerobic exercise on NVU biomarkers in individuals with MS. The study was conducted between February and June 2025 at the MS clinic affiliated with the Department of Neurology, Faculty of Medicine, Ondokuz Mayıs University. Participants were randomly assigned to either a control group or an exercise group. Assessments were conducted at baseline (pre-assessment) and eight weeks after the intervention (post-assessment).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 30 (actual)
- First submitted
- 2 Dec 2025
- Start date
- 1 Feb 2025
- Primary completion date
- 30 Jun 2025
- Lead sponsor
- Lokman Hekim University
- Diseases
- Multiple sclerosis
- NCT number
- NCT07325019
What you commit to
- Study type: Interventional
- Participants enrolled: 30
- From 1 Feb 2025 to the primary completion date, 30 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Having received immunomodulatory treatment within the last 6 months,
Other illness
- Having another known neuromuscular disorder besides MS,
- Having a cardiopulmonary disorder that could prevent participation in the exercise,
- Failure to attend three consecutive sessions of the exercise programme
- Development of a history of MS attacks or deterioration in health status
Other
- Having experienced an MS relapse within the last 6 months,
- Having an orthopaedic or systemic problem that would prevent participation in the exercises,
- Being pregnant or breastfeeding.
- Criteria for exclusion from the study:
- Change in ongoing pharmacological treatment or discontinuation of pharmacological treatment
Who the study is looking for
- Having a definite diagnosis of MS according to McDonald criteria,
- Being aged between 20 and 50,
- Having a Standardised Mini Mental Test (SMMT) score of ≥24,
- Having an Expanded Disability Status Scale (EDSS) score between 0 and 4.0,
- Having no other serious health problems that would prevent exercise,
- Having had no change in medication in the last 6 months.
Age in the registry: 20 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lokman Hekim University Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.