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NCT07326852Completed

Hybrid Assistive Limb Application in Multiple Sclerosis Patients

Effect of Hybrid Assistive Limb (HAL) Application on Locomotor Function and Balance Parameters in Multiple Sclerosis Patients

Source: ClinicalTrials.gov · Last updated 7 Jul 2026

Brief summary (registry, in English)

The Hybrid Assistive Limb (HAL) exoskeleton detects bioelectrical signals from the muscles, responds to the intention of voluntary movement, and provides biological feedback. In this study, the effects of HAL application on walking performance and balance in patients with multiple sclerosis will be examined in a single-center, controlled design. Participants will undergo walking rehabilitation with HAL for 1 hour per day, 5 days a week, for a total of 2 months. Walking and balance performance will be assessed before and after the intervention using the 10-Minute Walk Test (10MWT) to measure maximum walking speed, the 6-Minute Walk Test (6MWT) to evaluate walking endurance and cardiorespiratory performance, and the Timed Up and Go Test (TUG) to assess functional mobility and dynamic balance. Additionally, walking parameters and static balance will be measured using Tecnobody systems. Appropriate statistical tests will be applied, and a significance level of p\<0.05 will be considered.

Status (registry)
Completed
Study type
Interventional
Enrollment
13 (actual)
First submitted
18 Nov 2025
Start date
8 Oct 2025
Primary completion date
9 Dec 2025
Lead sponsor
Ege University
NCT number
NCT07326852

What you commit to

  • Study type: Interventional
  • Participants enrolled: 13
  • From 8 Oct 2025 to the primary completion date, 9 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of serious degenerative disease.
  • History of thoracic surgery.
  • Chronic respiratory diseases.
  • Presence of unstable cardiovascular disease.
  • Medical conditions that prevent mobilization.

Other

  • Presence of open wounds.

Who the study is looking for

  • No previous robotic rehabilitation.
  • Completion of the 10-meter walk test.
  • Mini mental status score ≥24.
  • MASS score \<2.
  • EDSS \<6.

Age in the registry: 18 years to 50 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Ege University
Coordinator of this site? Confirm its status
IzmirTurkey (Türkiye)Unknown status

This page is information, not medical advice. Discuss any trial with your doctor.