NCT07327138Recruiting
Children's Laughter and Fun Yoga as Adjunctive Pain Relief Following Chemotherapy.
A Multi-center, Assessor-blinded, Randomized, Parallel Group, Superiority Trial Evaluating the Efficacy of Home-based Laughter and Fun Yoga as an Adjunct for Pain Reduction in Pediatric Oncology Patients Receiving Chemotherapy.
Source: ClinicalTrials.gov · Last updated 8 Jan 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if a home-based program that combines laughter and fun yoga can help lower pain in children receiving chemotherapy. The study focuses on children with acute lymphoblastic leukemia who experience pain during treatment with chemotherapy and steroids. The main questions this study aims to answer are: 1. Does adding laughter and fun yoga to usual care lower pain levels in children receiving chemotherapy? 2. Does this program reduce the need for strong pain medicines, such as opioids? 3. Does the program help improve mood, anxiety, and sleep during treatment? Researchers will compare children who receive laughter and fun yoga plus usual care with children who receive usual care alone to see if the program works. Participants will: 1. Be randomly assigned to either the laughter and fun yoga group or the usual care group 2. Take part in the study during a 6-day period after receiving their chemotherapy treatment 3. Have their pain measured once each day using a child-friendly pain scale 4. Have parents answer short questions about pain medicine use, mood, anxiety, and sleep The laughter and fun yoga activities are gentle, safe, and designed to be done at home with the help of a parent. All participants will continue to receive their regular medical care throughout the study.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 25 Dec 2025
- Start date
- 15 Oct 2025
- Primary completion date
- 31 Oct 2026
- Lead sponsor
- Bahaa Bou Dargham
- NCT number
- NCT07327138
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 15 Oct 2025 to the primary completion date, 31 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent major surgery (within the past 2 weeks) that may limit safe participation in gentle activity.
Other illness
- Severe uncontrolled medical conditions (unstable vital signs, decompensated cardiac or respiratory disease, uncontrolled epilepsy) that may place the child at risk during light movement or laughter.
- Severe visual, hearing, or cognitive impairment preventing engagement with video-based instructions and exercises.
- Any other condition that, in the judgment of the treating physician, would interfere with safe participation or adherence.
Other
- Physical limitations or musculoskeletal injuries that prevent participation in the intervention.
- Currently enrolled in another interventional clinical trial for pain management.
Who the study is looking for
- Children aged 2-10 years.
- Medically diagnosed with acute lymphoblastic leukemia (ALL) and currently receiving chemotherapy that includes dexamethasone pulses during the maintenance phase.
- Clinically stable and able to participate in gentle, low-intensity yoga movements as determined by the treating physician.
- At least one parent or legal guardian willing and able to supervise and participate in the home-based intervention sessions.
- Written informed consent from parent/legal guardian, with age-appropriate assent from the child.
Age in the registry: 2 years to 10 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hammoud Hospital University Medical Center Coordinator of this site? Confirm its status | Sidon | Lebanon | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.