NCT07327749CompletedPhase 4
Comparing Bisoprolol and Valsartan-Amlodipine for Hypertension
Bisoprolol Monotherapy Versus Valsartan-Amlodipine for Hypertension Management in Adults Younger Than 60: Results of a Randomized Triple-Blind Clinical Trial
Source: ClinicalTrials.gov · Last updated 8 Jan 2026
Brief summary (registry, in English)
Randomized comparison of bisoprolol 2.5 mg monotherapy with fix combination drug valsartan 80 mg- amlodipine 5 mg
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 59 (actual)
- First submitted
- 26 Dec 2025
- Start date
- 1 Oct 2022
- Primary completion date
- 1 Dec 2024
- Lead sponsor
- Shiraz University of Medical Sciences
- Diseases
- High blood pressure
- NCT number
- NCT07327749
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 59
- From 1 Oct 2022 to the primary completion date, 1 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe hypertension (systolic blood pressure ≥ 180 mmHg or diastolic blood pressure ≥ 110 mmHg)
- Significant comorbidities requiring specific therapy such as diabetes or chronic heart failure, or current use of medications that could interact with the study drugs were excluded
- Individuals with suspected secondary hypertension, and those unable to adhere to follow-up procedures
Lab values
- Contraindication to calcium channel blocker
Other
- Contraindications to beta-blockers
- Contraindication to angiotensin receptor blockers
- Pregnant or breastfeeding women
Who the study is looking for
- newly diagnosed stage 1 or stage 2 hypertension confirmed by 24-hour ambulatory blood pressure monitoring (ABPM).
Age in the registry: 30 years to 59 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Professor Kojuri Cardiology Clinic Coordinator of this site? Confirm its status | Shiraz | Iran | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.