NCT07329751Not yet recruiting
Based on the Spatio-temporal Coding Characteristics of Frontotemporal Network, This Paper Explores the Mechanism of Five-tone Speech Training in Reshaping Language Fluency Function.
Source: ClinicalTrials.gov · Last updated 21 Jan 2026
Brief summary (registry, in English)
To explore the mechanism of five-tone speech training in reshaping language fluency function and the clinical efficacy of aphasia language function, daily communication ability and communication efficiency based on the temporal and spatial coding characteristics of frontotemporal network. Combined with EEG ( rsEEG, ERP ), nuclear magnetic resonance examination and near-infrared imaging system examination to explore its effect on brain electrophysiological activity. So as to promote the modernization of traditional Chinese medicine rehabilitation treatment technology and the popularization and application of speech rehabilitation treatment technology.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 28 Sept 2025
- Start date
- 31 Dec 2025
- Primary completion date
- 30 Sept 2027
- Lead sponsor
- Fujian University of Traditional Chinese Medicine
- Diseases
- Stroke
- NCT number
- NCT07329751
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 31 Dec 2025 to the primary completion date, 30 Sept 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Contraindications to MRI or fNIRS assessment (e.g., metallic implants, severe claustrophobia)
Other illness
- History of aphasia or neurological disease not caused by stroke (e.g., traumatic brain injury, brain tumor, neurodegenerative diseases)
- Severe cognitive impairment or disorders of consciousness preventing cooperation with language assessment or intervention
- History of epilepsy or other severe neurological conditions
- Severe systemic diseases (e.g., severe cardiopulmonary dysfunction, renal failure, hepatic failure, malignancy)
- Psychiatric disorders (e.g., schizophrenia, severe depression, or other major psychiatric illnesses)
Other
- Severe visual or auditory impairments that would interfere with task performance
- Severe dysarthria or apraxia of speech that precludes valid language assessment
Who the study is looking for
- Age between 18 and 70 years
- Right-handed
- Native Chinese speakers
- Clinical diagnosis of post-stroke aphasia caused by ischemic stroke, confirmed by CT or MRI
- Diagnosis of non-fluent aphasia based on the Western Aphasia Battery (WAB), with BDAE severity rating of 1-5
- Time since stroke onset ≥ 2 weeks
- Stable vital signs, clear consciousness, and no severe cognitive impairment
- Ability to understand the study procedures and provide written informed consent (or consent provided by a legally authorized representative)
Criteria the registry did not label
- Eligibility Criteria
Age in the registry: 18 years to 80 years · Sex: All · Accepts healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.