NCT07332234Recruiting
Optic Nerve Ultrasound for Assessing Cerebral Inflammation and Intracranial Hypertension in Cerebral Pathologies
Utility of Optic Nerve Ultrasonography in Assessing Cerebral Inflammation and Intracranial Hypertension in Patients With Cerebral Impairment
Source: ClinicalTrials.gov · Last updated 12 Jan 2026
Brief summary (registry, in English)
Timely detection of signs of raised intracranial pressure or persistent inflammation within the meninges can expedite therapeutic decisions improving the prognosis of patients with brain damage. Optic nerve ultrasonography provides a user-friendly, safe, low-cost, and non-invasive imaging method that can be easily deployed for ICU patient assessment. This study aims to evaluate the sensitivity and specificity of optic nerve ultrasound in estimating cerebral inflammation extension and cerebral edema in patients in the ICU. The working hypothesis is that optic nerve ultrasound is a useful tool in the rapid diagnosis of cerebral edema and the presence or persistence of cerebral inflammation, which can enable adapted and rapid therapeutic interventions.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 200 (estimated)
- First submitted
- 3 Dec 2025
- Start date
- Dec 2025
- Primary completion date
- Dec 2027
- Lead sponsor
- Spitalul Clinic de Boli Infecțioase și tropicale "Dr. Victor Babeș"
- Diseases
- Stroke, High blood pressure
- NCT number
- NCT07332234
What you commit to
- Study type: Observational
- Planned participants: 200
- From Dec 2025 to the primary completion date, Dec 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Ocular lesions preventing ocular ultrasound (palpebral infections, cornean erosions, glaucoma, trauma)
- Conditions preventing lumbar puncture (coagulation disorders, epidural abscesses, local infections)
Age
- Age under 18 years or over 60 years old
Who the study is looking for
- Patients admitted into one of the specified wards of the involved hospitals
- Patients aged 18-60 years
- Suspected meningitis, encephalitis, stroke or cerebral tumors
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| "Dr. Victor Babeș" Clinical Hospital for Infectious and Tropical Diseases Coordinator of this site? Confirm its status | Bucharest | Romania | Recruiting |
| Fundeni Clinical Institute Coordinator of this site? Confirm its status | Bucharest | Romania | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.