NCT07333456Completed
The Effects of Vibration on Lower Limb Muscle Strength, Functional Status, and Psychological Health in Stroke Patients
The Effects of Vibration on Lower Limb Muscle Strength, Functional Status, and Psychological Health in Stroke Patients.
Source: ClinicalTrials.gov · Last updated 10 Feb 2026
Brief summary (registry, in English)
The goal of this clinical trial is to the effect of vibration training on lower limb muscle strength, functional status and psychological health of stroke patients. The main questions it aims to answer are: * Lower limb muscle strength was measured using the Medical Research Council Manual Strength Test. * Functional status was measured using Postural Assessment Scale for Stroke, and the Barthel scale. * Psychological health was measured using the Hospital Anxiety and Depression Scale. Participants will be randomly assigned to four groups: 1. Control group: Receives only rehabilitation training and standard treatment. 2. Comparison group: Receives rehabilitation training, standard treatment, and a 30-minute stationary cycling intervention during hospitalization for 5 days. 3. Experimental group 1: Receives rehabilitation training, standard treatment, and a 30-minute wearable lower-limb high-frequency, low-amplitude vibration therapy during hospitalization for 5 days, followed by 30 minutes of stationary cycling. 4. Experimental group 2: Receives rehabilitation training, standard treatment, and a 30-minute vertical lower-limb low-frequency, high-amplitude vibration therapy during hospitalization for 5 days, followed by 30 minutes of stationary cycling. All participants will undergo an initial measurement within 4 hours of admission, followed by the second and third measurements after the 5-day intervention and on the day of discharge, respectively.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 115 (actual)
- First submitted
- 29 Sept 2025
- Start date
- 14 Jan 2022
- Primary completion date
- 26 Apr 2025
- Lead sponsor
- Tri-Service General Hospital (TSGH)
- Diseases
- Stroke
- NCT number
- NCT07333456
What you commit to
- Study type: Interventional
- Participants enrolled: 115
- From 14 Jan 2022 to the primary completion date, 26 Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Acute or chronic neurological or musculoskeletal injuries in the lower limbs or history of joint surgery within the past six months.
- Unstable or significant cardiovascular or cardiac disease, cancer history, end-stage renal disease requiring hemodialysis, or diagnosed psychiatric disorders, especially depression.
- Hospitalization exceeding 21 days due to other medical or surgical conditions (e.g., infections) or hospitalization shortened to fewer than seven days due to hospital transfers or seeking alternative therapies.
Other
- Diagnosed with transient ischemic attack (TIA) accompanied by vision or hearing impairments.
- Disability level of mRS ≥ 5 (severe disability requiring bedridden care).
- Presence of a pacemaker.
- Patients transferred from other hospital wards or intensive care units.
Who the study is looking for
- Hospitalized with a diagnosis of acute ischemic stroke (cerebral infarction).
- Stroke onset occurred within three days of admission.
- Age between 20 and 80 years old.
- Ability to communicate verbally or non-verbally and understand Mandarin or Taiwanese.
- Normal cognitive function (MMSE ≥ 21).
- Disability level assessed as 1-4 on the modified Rankin Scale (mRS)
- Willingness to participate in the study and agree to random group allocation.
Age in the registry: 20 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| TriServiceGH Coordinator of this site? Confirm its status | Taipei | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.