NCT07334626Completed
Impact of Pilates Exercises on Bone Mineral Density in Breast Cancer Survivors Receiving Hormonal Therapy
Source: ClinicalTrials.gov · Last updated 24 Jul 2026
Brief summary (registry, in English)
Breast cancer survivors receiving endocrine (hormonal) therapy (aromatase inhibitors) are at high risk for cancer treatment-induced bone loss and osteoporosis due to estrogen depletion.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 28 Dec 2025
- Start date
- 1 Jan 2026
- Primary completion date
- 20 Jul 2026
- Lead sponsor
- Benha University
- Diseases
- Osteoporosis
- NCT number
- NCT07334626
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 1 Jan 2026 to the primary completion date, 20 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current use of corticosteroids.
Other illness
- Metastatic (stage IV) or recurrent breast cancer.
- History of osteoporotic fractures in the past 12 months.
- Severe cardiovascular, respiratory, or musculoskeletal conditions that contraindicate exercise.
- Uncontrolled hypertension, diabetes, or thyroid disorders.
- Active bone metabolic disease other than osteoporosis (e.g., Paget's disease, osteomalacia).
- Severe cognitive impairment or psychiatric illness preventing adherence to exercise or supplementation.
Lab values
- Known allergy or intolerance to calcium or vitamin D supplementation.
Other
- Participation in another clinical trial with structured exercise or bone-targeted intervention within the last 3 months.
Who the study is looking for
- Female breast cancer survivors aged 40-60 years.
- Histologically confirmed stage I-III breast cancer.
- Currently receiving hormonal therapy (aromatase inhibitors) for at least 3 months.
- At risk of osteoporosis or with low bone mineral density (BMD) defined by T-score ≤ -1.0 at lumbar spine or hip.
- Medically cleared for exercise, specifically low-to-moderate intensity Pilates.
- Able to attend supervised exercise sessions three times per week for 12 weeks.
- Willing and able to provide written informed consent.
Age in the registry: 40 years to 60 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Outpatient clinic, faculty of Physical Therapy, Benha university Coordinator of this site? Confirm its status | Banhā | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.