NCT07334977RecruitingPhase 2
Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation
Synergistic Potential of Non-invasive Brain and Spinal Cord Stimulation for Improving Sensorimotor and Cognitive Functions After Neurological Injury
Source: ClinicalTrials.gov · Last updated 12 Jan 2026
Brief summary (registry, in English)
The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and cognitive functions after neurological injuries affecting the upper limb (cervical spinal cord injury and stroke). Secondary objectives are to evaluate the relevance of anatomical MRI, functional MRI, and neurophysiological measurements for optimizing and predicting the effects of these different interventions.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 45 (estimated)
- First submitted
- 28 Aug 2025
- Start date
- Dec 2024
- Primary completion date
- Jul 2027
- Lead sponsor
- Centre National de la Recherche Scientifique, France
- Diseases
- Stroke
- NCT number
- NCT07334977
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 45
- From Dec 2024 to the primary completion date, Jul 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Suffering from a chronic condition
- History of epilepsy or seizures
- Presence of a contraindication to the use of magnetic/electrical stimulation or MRI, including: cardiac pacemaker; implanted hearing aid; intraocular foreign body, shrapnel, or bullets; metal worker; pacemaker or neurostimulator; claustrophobia
- Presence of implanted medical devices (cardiac valve, endovascular devices, ventricular shunt valve, surgical clips, metallic sutures, staples, stent, osteosynthesis or arthrodesis hardware) not classified as "MR Conditional" according to ASTM F2503.
Other
- Skin problems or open wounds
- Individuals who are legally incompetent, under judicial protection, guardianship, or trusteeship
- Pregnant and/or breastfeeding women
- Individuals who refuse to be informed of any abnormalities that may be detected by MRI.
Who the study is looking for
- CONTROL GROUP:
- Over 18 years of age
- Participant who has signed an informed consent form
- Participant who is affiliated with and covered by the social security system
- POST-STROKE GROUP:
- Over 18 years of age
- Who sustained a stroke more than 3 weeks ago
- Considered medically stable by the medical investigator
- Who has signed an informed consent form
- Affiliated with and covered by the social security system
- SCI GROUP:
- Over 18 years of age
- Considered to have a complete or incomplete spinal cord injury (i.e., with a score on the Spinal Injury Association (ASIA) Impairment Scale (AIS) score from A to D)
- Considered medically stable by the investigating physician
- Presenting with quadriplegia due to cervical injury
- Who has signed an informed consent form
- Affiliated with and covered by the social security system.
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Service de Médecine Physique & Réadaptation - CHU Bordeaux Coordinator of this site? Confirm its status | Bordeaux | France | Recruiting |
| Centre de la Tour de Gassies Coordinator of this site? Confirm its status | Bruges | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.