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NCT07335692Recruiting

Dynamical Electrophysiology and Neuropathology in Lewy's Bodies Disease

Source: ClinicalTrials.gov · Last updated 13 Jan 2026

Brief summary (registry, in English)

Lewy body disease (LBD) is a neurodegenerative disorder that causes cognitive and behavioral problems. However, it is difficult to diagnose, and its pathophysiology is still not fully understood. The usual diagnostic criteria for LBD have excellent specificity but poor sensitivity. In particular, we lack paraclinical tests that can make a significant contribution. LBD patients may exhibit abnormalities in brain activity dynamics, which can be detected by EEG and may be linked to neuronal dysfunctions specific to the disease. The objective of this study is twofold: first, to assess the validity of this observation, that is, to confirm that the observed phenomenon is indeed linked to the pathophysiology of LBD, and second, to clarify the nature of these abnormalities by exploring the brain dynamics of LBD patients in greater detail.

Status (registry)
Recruiting
Study type
Observational
Enrollment
40 (estimated)
First submitted
2 Jan 2026
Start date
2 Jun 2025
Primary completion date
30 Jun 2026
Lead sponsor
University Hospital, Strasbourg, France
NCT number
NCT07335692

What you commit to

  • Study type: Observational
  • Planned participants: 40
  • From 2 Jun 2025 to the primary completion date, 30 Jun 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • \- Subject who expressed opposition to participating in the study.

Who the study is looking for

  • Adult subjects (≥18 years old).
  • Subject who participated in the Alpha-Lewy-MA cohort and underwent RT-QuIC analysis.
  • Subject who underwent a standard EEG examination at HUS between January 1, 2012, and January 1, 2020.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Service de psychiatrie de la personne âgée - CHU de Strasbourg - France
Coordinator of this site? Confirm its status
StrasbourgFranceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.