NCT07336316Enrolling by invitation
Multimodal Cardiovascular Magnetic Resonance Imaging for Cardiometabolic Pre-HF and HFpEF
Multimodal Cardiovascular Magnetic Resonance Imaging for Cardiometabolic Pre-HF and HFpEF: Integrated Phenotyping, Precision Diagnosis, and Risk Stratification
Source: ClinicalTrials.gov · Last updated 23 Jan 2026
Brief summary (registry, in English)
This is an observational study aiming to characterize the pathophysiological features and clinical significance of cardiometabolic early-stage heart failure using advanced multimodal cardiovascular magnetic resonance (CMR) imaging. The study will focus on patients with cardiometabolic risk factors such as diabetes, hypertension, and obesity who are in the pre-heart failure (pre-HF) stage or have heart failure with preserved ejection fraction (HFpEF). The study seeks to establish a full-chain imaging framework-from precise phenotypic classification and sensitive noninvasive diagnosis to individualized cardiovascular risk stratification. Participants will undergo multimodal CMR scans and comprehensive clinical evaluations and be followed up for primary outcome.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 3000 (estimated)
- First submitted
- 3 Jan 2026
- Start date
- 1 Jan 2010
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
- Diseases
- Heart failure, Obesity, High blood pressure
- NCT number
- NCT07336316
What you commit to
- Study type: Observational
- Planned participants: 3000
- From 1 Jan 2010 to the primary completion date, 31 Dec 2028
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Acute coronary syndrome in the previous 30 days
Other illness
- More than moderate valvular disease
- Restrictive pericardial disease
- Severe arrhythmia
- Heart tumors
- Infiltrative cardiomyopathy (e.g., cardiac amyloidosis)
- Congenital heart disease
Other
- Primary cardiomyopathy (e.g., hypertrophic, dilated, and restrictive cardiomyopathy)
- Poor image quality insufficient for delineating the endocardium and epicardium
Who the study is looking for
- Left ventricular ejection fraction (LVEF) ≥ 50%；
- Presence of cardiovascular risk factors, including, but not limited to, the following: diabetes mellitus, hypertension, obesity.
Sex: All · Accepts healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.