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NCT07336602Not yet recruiting

Neuroproprioceptive Equine-Assisted Physiotherapy for Spinal Muscular Atrophy

Immediate and Sustained Effects of Intensive Neuroproprioceptive Equine-Assisted Physiotherapy in Children With Spinal Muscular Atrophy: A Randomized Crossover Trial

Source: ClinicalTrials.gov · Last updated 13 Jan 2026

Brief summary (registry, in English)

This study investigates whether Equine-Assisted Physiotherapy based on Neuro-proprioceptive "Facilitation and Inhibition" (NEUROEQUIP-SMA) can improve movement, posture, breathing, and quality of life in children with spinal muscular atrophy (SMA). This therapy uses the horse's rhythmic movement together with targeted sensory and manual stimulation to trigger natural motor reactions starting from the pelvis, lower the threshold for muscle activation, and support coordinated motor patterns. The study compares this method with standard individual physiotherapy based on the same neuro-proprioceptive facilitation and inhibition principles, but performed without the horse. Twenty children aged 2 to 9 years will receive both therapies in two separate 6-day blocks, in random order (crossover design). The researchers will assess muscle fatigue, coordination, breathing function, movement quality and quantity, quality of life, and changes in selected blood biomarkers. The results may help develop better rehabilitation strategies for children with SMA who are receiving modern pharmacological or gene therapy.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
20 (estimated)
First submitted
19 Nov 2025
Start date
15 Apr 2026
Primary completion date
1 Jun 2026
Lead sponsor
Charles University, Czech Republic
NCT number
NCT07336602

What you commit to

  • Study type: Interventional
  • Planned participants: 20
  • From 15 Apr 2026 to the primary completion date, 1 Jun 2026
  • 4 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Known allergy to horses or the stable environment
  • Severe fear of horses that would prevent participation in equine-assisted physiotherapy
    • Any other medical condition that, in the investigator's opinion, would interfere with safe participation in the study

Other

  • Hip dislocation

Who the study is looking for

  • Age between 2 and 9 years
  • Clinical diagnosis of spinal muscular atrophy (SMA) type I, II, or III
  • Stable health condition for at least 6 months prior to enrollment
  • Ability to participate in the study procedures
  • Written informed consent provided by a parent or legal guardian

Age in the registry: 2 years to 9 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (4)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Mirákl Hippotherapy Center
Coordinator of this site? Confirm its status
BohuslaviceCzechiaUnknown status
College of Polytechnics Jihlava
Coordinator of this site? Confirm its status
JihlavaCzechiaUnknown status
Third Faculty of Medicine, Charles University
Coordinator of this site? Confirm its status
PragueCzechiaUnknown status
Department of Medical Genetics, Third Faculty of Medicine, Charles University
Coordinator of this site? Confirm its status
PragueCzechiaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.