NCT07336602Not yet recruiting
Neuroproprioceptive Equine-Assisted Physiotherapy for Spinal Muscular Atrophy
Immediate and Sustained Effects of Intensive Neuroproprioceptive Equine-Assisted Physiotherapy in Children With Spinal Muscular Atrophy: A Randomized Crossover Trial
Source: ClinicalTrials.gov · Last updated 13 Jan 2026
Brief summary (registry, in English)
This study investigates whether Equine-Assisted Physiotherapy based on Neuro-proprioceptive "Facilitation and Inhibition" (NEUROEQUIP-SMA) can improve movement, posture, breathing, and quality of life in children with spinal muscular atrophy (SMA). This therapy uses the horse's rhythmic movement together with targeted sensory and manual stimulation to trigger natural motor reactions starting from the pelvis, lower the threshold for muscle activation, and support coordinated motor patterns. The study compares this method with standard individual physiotherapy based on the same neuro-proprioceptive facilitation and inhibition principles, but performed without the horse. Twenty children aged 2 to 9 years will receive both therapies in two separate 6-day blocks, in random order (crossover design). The researchers will assess muscle fatigue, coordination, breathing function, movement quality and quantity, quality of life, and changes in selected blood biomarkers. The results may help develop better rehabilitation strategies for children with SMA who are receiving modern pharmacological or gene therapy.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 19 Nov 2025
- Start date
- 15 Apr 2026
- Primary completion date
- 1 Jun 2026
- Lead sponsor
- Charles University, Czech Republic
- Diseases
- Spinal muscular atrophy
- NCT number
- NCT07336602
What you commit to
- Study type: Interventional
- Planned participants: 20
- From 15 Apr 2026 to the primary completion date, 1 Jun 2026
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known allergy to horses or the stable environment
- Severe fear of horses that would prevent participation in equine-assisted physiotherapy
- Any other medical condition that, in the investigator's opinion, would interfere with safe participation in the study
Other
- Hip dislocation
Who the study is looking for
- Age between 2 and 9 years
- Clinical diagnosis of spinal muscular atrophy (SMA) type I, II, or III
- Stable health condition for at least 6 months prior to enrollment
- Ability to participate in the study procedures
- Written informed consent provided by a parent or legal guardian
Age in the registry: 2 years to 9 years · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mirákl Hippotherapy Center Coordinator of this site? Confirm its status | Bohuslavice | Czechia | Unknown status |
| College of Polytechnics Jihlava Coordinator of this site? Confirm its status | Jihlava | Czechia | Unknown status |
| Third Faculty of Medicine, Charles University Coordinator of this site? Confirm its status | Prague | Czechia | Unknown status |
| Department of Medical Genetics, Third Faculty of Medicine, Charles University Coordinator of this site? Confirm its status | Prague | Czechia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.