NCT07336693Completed
Bone Density Change in Postmenopausal Rheumatoid Arthritis
Changes in Bone Mineral Density and the Impact of Therapeutic Approaches in Postmenopausal Patients With Rheumatoid Arthritis
Source: ClinicalTrials.gov · Last updated 13 Jan 2026
Brief summary (registry, in English)
Rheumatoid arthritis is associated with systemic inflammation-mediated bone loss, leading to an increased risk of osteoporosis and fractures, particularly in postmenopausal patients. Although disease-modifying antirheumatic drugs may help mitigate bone loss, comparative longitudinal data on different treatment strategies remain limited. This study aimed to evaluate changes in bone mineral density over time and assess the impact of conventional synthetic and biologic DMARDs, together with anti-osteoporotic therapy, on bone health.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 82 (actual)
- First submitted
- 2 Jan 2026
- Start date
- 1 Jun 2025
- Primary completion date
- 1 Sept 2025
- Lead sponsor
- Istanbul University - Cerrahpasa
- Diseases
- Rheumatoid arthritis, Osteoporosis
- NCT number
- NCT07336693
What you commit to
- Study type: Observational
- Participants enrolled: 82
- From 1 Jun 2025 to the primary completion date, 1 Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concomitant inflammatory rheumatic diseases other than RA
Other illness
- History of malignancy
- Uncontrolled or untreated endocrine or metabolic disorders affecting bone metabolism, such as primary hyperparathyroidism, Cushing's syndrome, severe renal failure, severe hepatic failure
Other
- Incomplete medical records or missing data
Who the study is looking for
- Postmenopausal women with a confirmed diagnosis of rheumatoid arthritis
Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Istanbul University - Cerrahpasa (IUC) Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.