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NCT07337434RecruitingEarly phase 1

To Check Comparison of Apremilast and Methotrexate Efficacy in Patients With Moderate to Severe Plaque Psoriasis Presented to Tertiary Care Hospital

Comparison of Efficacy of Methotrexate vs Apremilast in Moderate to Severe Plaque Psoriasis

Source: ClinicalTrials.gov · Last updated 13 Jan 2026

Brief summary (registry, in English)

This study aims to compare efficacy of methotrexate vs apremilast in the management of chronic plaque psoriasis.Given the high prevalence of psoriasis in Pakistan and the significant psychological impact on patients, particularly in Peshawer,this study will provide valuable insights into optimal treatment strategies.

Status (registry)
Recruiting
Phase (registry)
Early phase 1
Study type
Interventional
Enrollment
106 (estimated)
First submitted
17 Dec 2025
Start date
Dec 2025
Primary completion date
Jun 2026
Lead sponsor
Syeda Sana Zaman
Diseases
Psoriasis
NCT number
NCT07337434

What you commit to

  • Study type: Interventional · Early phase 1
  • Planned participants: 106
  • From Dec 2025 to the primary completion date, Jun 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Pregnancy or lactation History of liver or renal dysfunction Known hypersensitivity to study drugs

Who the study is looking for

  • Patients having age between 18-60 years of either gender Diagnosed with moderate to severe plaque psoriasis (PASI ≥10) No prior systemic therapy in past 3 months.

Age in the registry: 18 years to 60 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
MTI-HMC Peshawar
Coordinator of this site? Confirm its status
PeshawarPakistanRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.