NCT07341243Recruiting
Exercising in Hot Conditions: How Does it Effect Blood Glucose in People With T1D
The Effect of Acute Heat Exposure on Glucose Use During Moderate-intensity Exercise in People With Type 1 Diabetes
Source: ClinicalTrials.gov · Last updated 14 Jan 2026
Brief summary (registry, in English)
A randomised, crossover, counterbalanced repeated measures study will be conducted to examine the effect of acute heat exposure on rate of change in blood glucose concentration during 40 minutes of moderate-intensity exercise and for 30 minutes after exercise. Participants will complete two experimental conditions during two separate laboratory visits, with the order of conditions randomised. One condition will be a temperate condition of 20°C with 50% relative humidity (Temperate), the other will be 40°C with 50% relative humidity (Heat). Visits will be identical, including time of day, except for the condition. Visits will be separated by 24h. Testing will take place in the laboratories of the Research Institute for Sport and Exercise Sciences at Liverpool John Moores University.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 38 (estimated)
- First submitted
- 25 Nov 2025
- Start date
- 1 Nov 2025
- Primary completion date
- 1 Nov 2026
- Lead sponsor
- Liverpool John Moores University
- Diseases
- Type 1 diabetes
- NCT number
- NCT07341243
What you commit to
- Study type: Interventional
- Planned participants: 38
- From 1 Nov 2025 to the primary completion date, 1 Nov 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- \<6 months postpartum or stopped breastfeeding \<1 month before recruitment
Other illness
- Existing cerebrovascular or cardiovascular disease
- History of severe hypoglycaemia requiring third party assistance within the last 3 months
- Obstructive gastrointestinal disease
- History of gastrointestinal surgery
Lab values
- Significant history of hyperglycaemia (HbA1c \>85 mmol/mol)
Other
- Pregnancy
- Body weight \<36.5kg
- Difficulty swallowing tablets
- Appointment for an MRI test that cannot be rescheduled
- Have an implanted medical device
Who the study is looking for
- T1D diagnosis more than 1 years ago (to ensure participants are out of the honeymoon period)
- Using insulin therapy with multiple daily injections (MDI), insulin pump (pump), or hybrid closed-loop (HCL)
- o If using a HCL system have experience of using a pre-programmed basal rate in manual mode during exercise
- Aged 18-65 years
- Regularly engaged in endurance exercise (training at least twice per week for ≥30 minutes per session)
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Liverpool John Moores University Coordinator of this site? Confirm its status | Liverpool | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.