NCT07341711Recruiting
Long-term Adaptations of Skeletal Muscle After Hybrid Training
Long-term Adaptations of Skeletal Muscle in Overweight and Obese Individuals After Hybrid Training
Source: ClinicalTrials.gov · Last updated 12 Jun 2026
Brief summary (registry, in English)
Obesity is a major challenge for public health and renders it imperative to reduce its prevalence. High intensity interval training (HIIT) is a form of exercise training that can efficiently induce weight loss in adults with overweight or obesity, even in the absence of dietary intake manipulation. Hybrid type training represents a form of HIIT, that incorporates both cardiorespiratory and musculoskeletal stimuli, by combining multiple types of exercise into a circuit-type, interval style workout. Recent evidence suggests that long-term participation in hybrid HIIT results in significant health-related benefits. However, the molecular mechanisms driving the chronic effects of hybrid HIIT on cardiometabolic and musculoskeletal health remains to be elucidated.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 5 Jan 2026
- Start date
- 8 Jan 2026
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- University of Thessaly
- Diseases
- Obesity
- NCT number
- NCT07341711
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 8 Jan 2026 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Cosumption of anti-inflammatory of pain relief medication
Other
- Low participation rate (\<80% completion of the exercise training sessions)
- Unbalanced diet
- Participation in additional exercise training regimes
Who the study is looking for
- BMI: \>25 kg/m2 and \<40 kg/m2
- Untrained individuals (abstain \>1 year from exercise training)
- No dietary intervention over the last 6 months preceding the study
- Low cardiorespiratory fitness level (VO2max: \<45 ml/kg/min)
- No use of any medication, dietary supplements
- Low risk for cardiovascular disease
- A weight loss \<10% over the last 6 months preceding the study
- Free of non-communicable diseases (excluding metabolic syndrome)
Age in the registry: 30 years to 50 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Physical Education and Sport Science Trikala, University of Thessaly Coordinator of this site? Confirm its status | Trikala | Greece | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.