NCT07341984Recruiting
A Physiotherapy Intervention Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
Individualized Physiotherapy Addressing Patient-Specific Deficits in Amyotrophic Lateral Sclerosis Compared to Usual Care Physiotherapy: A Prospective, Pseudorandomized, Controlled, Interventional Study
Source: ClinicalTrials.gov · Last updated 15 Jan 2026
Brief summary (registry, in English)
This study investigates whether an individualized physiotherapy program, tailored to each patient's specific motor deficits, can better support physical function compared with usual care physiotherapy in people with ALS. The individualized program is guided by diagnostic assessments using a robotic leg press system, which helps identify strengths and weaknesses in muscle function and movement control. Participants will receive either individualized physiotherapy or standard physiotherapy and will be followed for 12 months. The aim of the study is to improve physiotherapy strategies for people with ALS in a safe and patient-centered manner.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 38 (estimated)
- First submitted
- 6 Jan 2026
- Start date
- 16 Dec 2025
- Primary completion date
- 15 Dec 2027
- Lead sponsor
- Charlotte Vogt
- Diseases
- ALS (motor neurone disease)
- NCT number
- NCT07341984
What you commit to
- Study type: Interventional
- Planned participants: 38
- From 16 Dec 2025 to the primary completion date, 15 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- concomitant life-threatening disease or impairment interfering with functional assessment
Other illness
- pregnancy, tracheostomy, continuous assisted ventilation, or other significant non-ALS pulmonary disease
- other neurodegenerative or neuromuscular conditions that may confound assessments
Who the study is looking for
- diagnosis of clinically probable, probable laboratory-supported, or definite ALS (revised El Escorial criteria) or upper motor neuron only (OPM classification \[onset, propagation, motoneuron involvement\])
- age ≥18 years; ability to understand study information and provide written informed consent
- Willingness and ability to perform individualized exercise according to the study protocol (approximately three to five sessions of 30 minutes per week) for the duration of the intervention period
- Individuals of all sexes and gender identities are eligible for inclusion
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| ALS Clinic Coordinator of this site? Confirm its status | Sankt Gallen | Switzerland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.