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NCT07345247Recruiting

RAdiation SEgmentectomy With REsin Microspheres (RASEREM) Study

Source: ClinicalTrials.gov · Last updated 22 Jan 2026

Brief summary (registry, in English)

Radiation segmentectomy (RS) refers to selective infusion of Y-90 microspheres to the tumor bearing hepatic segment of hepatic artery. Majority of the data on RS is based on the Glass microspheres experience. Due to different properties of Resin and Glass microspheres description of dose limits to the segment for effectiveness of treatments with Resin microspheres are needed. Based on this background in this study it is aimed to evaluate the safety and efficacy of RS with resin microspheres in HCC patients. Secondly, it is planned to describe the dose limits for complete radiological response.

Status (registry)
Recruiting
Study type
Observational
Enrollment
150 (estimated)
First submitted
28 Dec 2025
Start date
1 Aug 2025
Primary completion date
1 Mar 2028
Lead sponsor
Ankara University
NCT number
NCT07345247

What you commit to

  • Study type: Observational
  • Planned participants: 150
  • From 1 Aug 2025 to the primary completion date, 1 Mar 2028
  • 20 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Presence of extrahepatic disease,

Other

  • Presence of macrovascular invasion,
  • Cholangiocarcinoma or mixed HCC-cholangiocarcinoma
  • Not willing to attend follow-up visits.

Who the study is looking for

  • Patients aged ≥18 years
  • Underwent RE as a RS intent (have single or \<3 tumors in same or neighboring 2 segments) for the treatment of HCC or metastatic tumor to liver.
  • Presence of extrahepatic disease
  • Tumor size less than 8 cm
  • Child Pugh Score \<B9

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (20)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Adana City Hospital
Coordinator of this site? Confirm its status
AdanaTurkey (Türkiye)Not yet recruiting
Cukurova University
Coordinator of this site? Confirm its status
AdanaTurkey (Türkiye)Not yet recruiting
Acibadem Adana Hospital
Coordinator of this site? Confirm its status
AdanaTurkey (Türkiye)Recruiting
Gulhane Education and Research Hospital
Coordinator of this site? Confirm its status
AnkaraTurkey (Türkiye)Not yet recruiting
Bilkent City Hospital
Coordinator of this site? Confirm its status
AnkaraTurkey (Türkiye)Not yet recruiting
Hacettepe University
Coordinator of this site? Confirm its status
AnkaraTurkey (Türkiye)Recruiting
Pamukkale University
Coordinator of this site? Confirm its status
DenizliTurkey (Türkiye)Not yet recruiting
Gazi Yasargil Education and Research Hospital
Coordinator of this site? Confirm its status
DiyarbakırTurkey (Türkiye)Not yet recruiting
Istanbul University Capa Medical School
Coordinator of this site? Confirm its status
IstanbulTurkey (Türkiye)Recruiting
Marmara University
Coordinator of this site? Confirm its status
IstanbulTurkey (Türkiye)Recruiting
Istanbul Unicersity Cerrahpasa Medical School
Coordinator of this site? Confirm its status
IstanbulTurkey (Türkiye)Not yet recruiting
Cam ve Sakura Education and Reseach Hospital
Coordinator of this site? Confirm its status
IstanbulTurkey (Türkiye)Recruiting
Acibadem Izmir Hospital
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IzmirTurkey (Türkiye)Not yet recruiting
Ege University
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IzmirTurkey (Türkiye)Not yet recruiting
Katip Celebi Education and Research Hospital
Coordinator of this site? Confirm its status
IzmirTurkey (Türkiye)Recruiting
Erciyes University
Coordinator of this site? Confirm its status
KayseriTurkey (Türkiye)Recruiting
Kocaeli University
Coordinator of this site? Confirm its status
KocaeliTurkey (Türkiye)Not yet recruiting
Konya Selcuk University
Coordinator of this site? Confirm its status
KonyaTurkey (Türkiye)Recruiting
Inonu University
Coordinator of this site? Confirm its status
MalatyaTurkey (Türkiye)Recruiting
Mersin City Hospital
Coordinator of this site? Confirm its status
MersinTurkey (Türkiye)Not yet recruiting

This page is information, not medical advice. Discuss any trial with your doctor.