NCT07345247Recruiting
RAdiation SEgmentectomy With REsin Microspheres (RASEREM) Study
Source: ClinicalTrials.gov · Last updated 22 Jan 2026
Brief summary (registry, in English)
Radiation segmentectomy (RS) refers to selective infusion of Y-90 microspheres to the tumor bearing hepatic segment of hepatic artery. Majority of the data on RS is based on the Glass microspheres experience. Due to different properties of Resin and Glass microspheres description of dose limits to the segment for effectiveness of treatments with Resin microspheres are needed. Based on this background in this study it is aimed to evaluate the safety and efficacy of RS with resin microspheres in HCC patients. Secondly, it is planned to describe the dose limits for complete radiological response.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 150 (estimated)
- First submitted
- 28 Dec 2025
- Start date
- 1 Aug 2025
- Primary completion date
- 1 Mar 2028
- Lead sponsor
- Ankara University
- Diseases
- Liver and biliary tract cancer
- NCT number
- NCT07345247
What you commit to
- Study type: Observational
- Planned participants: 150
- From 1 Aug 2025 to the primary completion date, 1 Mar 2028
- 20 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of extrahepatic disease,
Other
- Presence of macrovascular invasion,
- Cholangiocarcinoma or mixed HCC-cholangiocarcinoma
- Not willing to attend follow-up visits.
Who the study is looking for
- Patients aged ≥18 years
- Underwent RE as a RS intent (have single or \<3 tumors in same or neighboring 2 segments) for the treatment of HCC or metastatic tumor to liver.
- Presence of extrahepatic disease
- Tumor size less than 8 cm
- Child Pugh Score \<B9
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (20)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Adana City Hospital Coordinator of this site? Confirm its status | Adana | Turkey (Türkiye) | Not yet recruiting |
| Cukurova University Coordinator of this site? Confirm its status | Adana | Turkey (Türkiye) | Not yet recruiting |
| Acibadem Adana Hospital Coordinator of this site? Confirm its status | Adana | Turkey (Türkiye) | Recruiting |
| Gulhane Education and Research Hospital Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Not yet recruiting |
| Bilkent City Hospital Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Not yet recruiting |
| Hacettepe University Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Recruiting |
| Pamukkale University Coordinator of this site? Confirm its status | Denizli | Turkey (Türkiye) | Not yet recruiting |
| Gazi Yasargil Education and Research Hospital Coordinator of this site? Confirm its status | Diyarbakır | Turkey (Türkiye) | Not yet recruiting |
| Istanbul University Capa Medical School Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Recruiting |
| Marmara University Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Recruiting |
| Istanbul Unicersity Cerrahpasa Medical School Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Not yet recruiting |
| Cam ve Sakura Education and Reseach Hospital Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Recruiting |
| Acibadem Izmir Hospital Coordinator of this site? Confirm its status | Izmir | Turkey (Türkiye) | Not yet recruiting |
| Ege University Coordinator of this site? Confirm its status | Izmir | Turkey (Türkiye) | Not yet recruiting |
| Katip Celebi Education and Research Hospital Coordinator of this site? Confirm its status | Izmir | Turkey (Türkiye) | Recruiting |
| Erciyes University Coordinator of this site? Confirm its status | Kayseri | Turkey (Türkiye) | Recruiting |
| Kocaeli University Coordinator of this site? Confirm its status | Kocaeli | Turkey (Türkiye) | Not yet recruiting |
| Konya Selcuk University Coordinator of this site? Confirm its status | Konya | Turkey (Türkiye) | Recruiting |
| Inonu University Coordinator of this site? Confirm its status | Malatya | Turkey (Türkiye) | Recruiting |
| Mersin City Hospital Coordinator of this site? Confirm its status | Mersin | Turkey (Türkiye) | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.