NCT07345702Recruiting
Basilar Artery Occlusion Chinese Endovascular Registry in Patients With Large-Core Infarct
Endovascular Versus Medical Therapy for Acute Large-Core Basilar Artery Occlusion: A Multicenter Retrospective Registry Study (BAOCHE-LC)
Source: ClinicalTrials.gov · Last updated 30 Jul 2026
Brief summary (registry, in English)
This multicenter retrospective registry study evaluates the safety and effectiveness of endovascular therapy versus medical therapy for acute large-core basilar artery occlusion. It also investigates clinical, imaging, and laboratory factors associated with functional outcomes and mortality. Patients are grouped according to the treatment received in routine clinical practice.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 518 (estimated)
- First submitted
- 7 Jan 2026
- Start date
- 31 Jan 2026
- Primary completion date
- 31 Oct 2026
- Lead sponsor
- Xuanwu Hospital, Beijing
- Diseases
- Stroke
- NCT number
- NCT07345702
What you commit to
- Study type: Observational
- Planned participants: 518
- From 31 Jan 2026 to the primary completion date, 31 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- CT or MR evidence of hemorrhage (the presence of microbleeds on MRI is allowed).
- Any other condition judged by investigators to substantially affect analysis or interpretation.
Other
- Subjects with occlusions in both anterior and posterior circulation.
- Missing key clinical information (e.g., unavailable baseline NIHSS, unclear symptom onset/last known well time, or missing major treatment information including whether EVT was performed).
- Baseline NIHSS score \<6.
- Woman of childbearing potential who is known to be pregnant or lactating or who has a positive pregnancy test on admission.
- Missing follow-up outcomes at 90 days.
Who the study is looking for
- Age ≥18 years, men or women.
- Occlusion (TIMI 0-1) of the basilar artery or intracranial segments of both vertebral arteries (V4) as evidenced by CTA/MRA/DSA.
- Time from symptom onset (or last known well) to treatment (endovascular therapy or medical therapy) ≤7 days.
- Patients with large core infarction in the posterior circulation, defined as a posterior circulation Acute Stroke Prognosis Early CT score (pc-ASPECTS) score of 0-5 on CT angiography source images or MR with diffusion-weighted imaging or non-contrast CT.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Xuanwu Hospital Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.