NCT07345858Enrolling by invitation
Salivary Oxytocin as a Biomarker of Psychedelic Treatment
Salivary Oxytocin as a Biomarker of Psychedelic Assisted Psychotherapy in Patients With Major Depressive Disorder
Source: ClinicalTrials.gov · Last updated 16 Jan 2026
Brief summary (registry, in English)
This study aims to investigate whether oxytocin reactivity during a psychedelic session for MDD treatment predicts treatment response, specifically by examining its relationship with changes in flexibility and depressive symptoms.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 80 (estimated)
- First submitted
- 7 Jan 2026
- Start date
- 5 Jan 2026
- Primary completion date
- 31 Jul 2026
- Lead sponsor
- University of Geneva, Switzerland
- Diseases
- Depression
- NCT number
- NCT07345858
What you commit to
- Study type: Observational
- Planned participants: 80
- From 5 Jan 2026 to the primary completion date, 31 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Psychotic or bipolar disorder
- Severe cardiovascular, hepatic or neurological (affecting the central nervous system) disorders
Other
- High suicidal risk
- Pregnancy or breastfeeding.
Who the study is looking for
- Age \>=18 years-old
- MDD defined by DSM-V criteria, and resistant to treatment
- Ongoing classical psychotherapeutic treatment
- Agreement to discontinue necessary psychotropic medications (some classes of anti-depressants are allowed with no need to taper off).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Geneva University Hospitals Coordinator of this site? Confirm its status | Geneva | Switzerland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.