NCT07346924Completed
Effect of Probiotics on Relapsing-Remitting Multiple Sclerosis
Probiotics as a Promising Adjunct: Improving Fatigue, Quality of Life, Disability, Mood and Inflammatory Markers in Egyptian Relapsing-Remitting Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 8 Jun 2026
Brief summary (registry, in English)
This study aimed to assess the effect of probiotic supplementation on fatigue, quality of life, disability, depression and inflammatory markers in patients with relapsing-remitting multiple sclerosis (RRMS). Patients were randomized to receive probiotics plus standard therapy The study sought to determine whether modulation of gut microbiota could provide additional clinical and immunological benefits in RRMS management.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 25 Dec 2025
- Start date
- 1 Jan 2024
- Primary completion date
- 1 Sept 2024
- Lead sponsor
- Cairo University
- Diseases
- Multiple sclerosis
- NCT number
- NCT07346924
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 1 Jan 2024 to the primary completion date, 1 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who had relapses and glucocorticoid therapy within the past 30 days.
- Pregnancy and women who were lactating within the prior six month
- Patients who have changed their disease modifying drugs in the past 6 months prior to study
- Impaired cognition that limited ability to complete the questionnaires. Addiction to drugs or alcohol.
Other illness
- History of gastroenteritis and bowel surgery over the past month, inflammatory bowel disease
- Presence of diabetes (type I \& type II) or diseases causing significant nutritional status impairment (malignancy, chronic infections)
Other
- Progressive MS either; primary progressive MS or secondary progressive MS
- Patients taking antibiotics
Who the study is looking for
- Clinically definite MS patients with a diagnosis of relapsing remitting multiple sclerosis according to revised McDonald criteria 2017.
- EDSS score of ≤ 4
Age in the registry: 20 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of medicine Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.