NCT07347327Completed
The Effect of Dual-target tACS Combined With Speech Training on Repetition Disorder After Stroke
Source: ClinicalTrials.gov · Last updated 22 Jan 2026
Brief summary (registry, in English)
This clinical trial aims to study whether dual-target transcranial alternating current stimulation (tACS) applied to the auditory and motor brain region can improve repetition disorder in people with stroke, and to evaluate the safety of tACS. The main goals are to answer the following questions: 1. Can dual-tACS stimulation of the auditory and motor brain area improve repetition functions in people with aphasia after stroke? 2. Can it improve the integration of auditory information and speech motor control during communication? Researchers will compare the effects of real tACS versus sham (placebo) stimulation to see if real stimulation leads to better outcomes in aphasia patients. Participants will: 1. Receive one extra 20-minute session of either real or sham tACS each day for 10 days 2. Attend clinic visits before and after 10-days stimulation for clinical assessments(WAB) and fNIRS recording related brain activity
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 28 (actual)
- First submitted
- 9 Jan 2026
- Start date
- Jan 2023
- Primary completion date
- Dec 2025
- Lead sponsor
- Ke Dong, MD
- Diseases
- Stroke
- NCT number
- NCT07347327
What you commit to
- Study type: Interventional
- Participants enrolled: 28
- From Jan 2023 to the primary completion date, Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently receiving non-invasive brain stimulation treatment;
Other illness
- History of epilepsy, mental illness,or other neurological or mental disorders;
Other
- Lesions involving the Broca or STG brain regions;
- Any contraindications for transcranial electrical stimulation.
Who the study is looking for
- Meeting the diagnostic criteria for hemorrhagic or ischemic stroke in the Chinese Guidelines for the Prevention and Treatment of Cerebrovascular Diseases(2nd edition), with the first onset, single hemisphere stroke, and confirmed by CT or MRI,course of diease 1-6 months;
- Age ranging from 30 to 80 years old;
- Native language is Mandarin or Cantonese;
- Right-handed;
- Diagnosed with aphasia by the Western Aphasia Battery (WAB) scale;
- Able to cooperate in completing the speech repetition test;
- Normal hearing.
Age in the registry: 30 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University Coordinator of this site? Confirm its status | Guangzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.