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NCT07347431Recruiting

Large Language Model for Understanding and Monitoring Elderly Neurocognition

LUMEN (Large Language Model for Understanding and Monitoring Elderly Neurocognition): A Clinical Feasibility Study With Nested Qualitative Evaluation for AI- Assisted Dementia Assessment

Source: ClinicalTrials.gov · Last updated 21 Apr 2026

Brief summary (registry, in English)

Dementia affects millions of people worldwide, and early diagnosis is essential for getting the right care and support. Doctors rely on collateral histories (accounts from family members or caregivers) to understand changes in a person's memory and thinking. However, these histories can be incomplete, unstructured, or difficult to obtain, making diagnosis more challenging. This study will test LUMEN (Large Language Model for Understanding and Monitoring Elderly Neurocognition), an AI-powered conversation tool designed to help caregivers describe their loved one's symptoms more effectively. By asking structured questions and guiding the conversation, LUMEN can create clear, well-organised reports for memory clinic doctors. This could make assessments quicker, more accurate, and less stressful for families. We will test LUMEN in real-world clinics by asking caregivers and doctors to use it and provide feedback. We want to understand how easy it is to use, whether it could improve the quality of information shared, and how it fits into existing NHS memory clinic processes. We will also run co-production workshops with community groups to ensure the tool is accessible to people from diverse cultural and language backgrounds. This research is exciting because it explores how artificial intelligence can improve dementia care. If successful, LUMEN could enhance the diagnostic process, reduce carer burden, and help more people access dementia support sooner. In the future, this tool could be used nationwide in memory clinics, improving care for thousands of families.

Status (registry)
Recruiting
Study type
Observational
Enrollment
60 (estimated)
First submitted
8 Jan 2026
Start date
19 Mar 2026
Primary completion date
31 Dec 2026
Lead sponsor
Northumbria Healthcare NHS Foundation Trust
NCT number
NCT07347431

What you commit to

  • Study type: Observational
  • Planned participants: 60
  • From 19 Mar 2026 to the primary completion date, 31 Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Criteria the registry did not label

  • Carers of patients attending Memory Clinic appointments; Aged 18 or over; Both patients and cares can provide informed consent; Basic English literacy
  • Clinicians must have at least 2 years of specialist dementia care experience and be personally responsible for dementia diagnosis; Must be provide informed consent

Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
North Tyneside General Hospital is Rake Lane
Coordinator of this site? Confirm its status
North ShieldsUnited KingdomRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.