NCT07348718Active, not recruiting
Rubix LS Diabetic Kidney Disease (DKD) Registry Study
Rubix LS DKD Equity Registry (RUBIX-DKD): A Prospective Observational Patient Registry to Characterize Diabetic Kidney Disease Trajectories, Treatment Patterns, and Outcomes in Underserved Communities and to Enable a Future Embedded Phase IV Pragmatic Study
Source: ClinicalTrials.gov · Last updated 16 Jan 2026
Brief summary (registry, in English)
Diabetic kidney disease (DKD) is a common complication of type 2 diabetes that can lead to kidney failure and increases the risk of cardiovascular disease. This prospective, observational patient registry will follow adults with type 2 diabetes and DKD who are receiving routine clinical care at participating sites, with intentional enrollment from underserved communities. Health information will be collected from medical records and brief questionnaires (including social and access factors) for up to 24 months to understand DKD progression, real-world treatment patterns, and outcomes. This study does not assign any treatment. With participant consent and appropriate privacy safeguards, de-identified registry data may be shared with researchers to accelerate evidence generation and inform future studies focused on improving outcomes.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 2000 (estimated)
- First submitted
- 8 Jan 2026
- Start date
- 15 Dec 2025
- Primary completion date
- 31 Mar 2026
- Lead sponsor
- Rubix LS
- Diseases
- Chronic kidney disease, Type 2 diabetes
- NCT number
- NCT07348718
What you commit to
- Study type: Observational
- Planned participants: 2000
- From 15 Dec 2025 to the primary completion date, 31 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- End-stage kidney disease at baseline (maintenance dialysis) or history of kidney transplant
- Type 1 diabetes mellitus
- Known primary kidney disease not primarily attributable to diabetes that, in the investigator's judgment, is expected to drive kidney outcomes (e.g., polycystic kidney disease, active glomerulonephritis, lupus nephritis, vasculitis)
Other
- Inability to provide informed consent or comply with registry procedures (e.g., no feasible longitudinal follow-up through the participating site)
Who the study is looking for
- Age ≥18 years at the time of enrollment
- Documented diagnosis of type 2 diabetes mellitus in the medical record
- Evidence of chronic kidney disease consistent with diabetic kidney disease (DKD), defined by one or more of the following, with evidence of chronicity (present for ≥3 months based on prior laboratory results, diagnosis codes, or clinician documentation):
- eGFR \<60 mL/min/1.73 m², and/or
- Urine albumin-to-creatinine ratio (UACR) ≥30 mg/g
- Receiving ongoing clinical care at a participating site with medical record data available for longitudinal follow-up
- Able and willing to provide written informed consent (and authorization for medical record review, as applicable) and to complete registry questionnaires
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rubix LS Coordinator of this site? Confirm its status | Lawrence | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.