NCT07351032Recruiting
Understanding How Movements Are Transferred From Task to Task in Parkinson's Disease
Neural Mechanism of Skill Transfer in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 20 Jan 2026
Brief summary (registry, in English)
The purpose of this study is to understand how a specific brain area, the Posterior Parietal Cortex (PPC), plays a role in movement transfer from walking on a split-belt treadmill (SBT) to walking on the ground in people with Parkinson's disease (PwPD). Here, investigators will apply repeated transcranial magnetic stimulation (rTMS) to upregulate the PPC. Then, the differences in the gait parameters between pre- and post-interventions will be compared between the TMS-active and the TMS-sham.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- First submitted
- 26 Sept 2025
- Start date
- 18 Nov 2025
- Primary completion date
- May 2026
- Lead sponsor
- McGill University
- Diseases
- Parkinson disease
- NCT number
- NCT07351032
What you commit to
- Study type: Interventional
- Planned participants: 24
- From 18 Nov 2025 to the primary completion date, May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- severe dyskinesia that interacts with walking and balance hearing or visual impairment
- neurological disorders other than PD or other pathology (e.g., orthopedic) interfering with mobility. - contradiction for TMS
Other
- observed inability to walk safely on a tied-belt treadmill
- implanted deep brain stimulator.
Who the study is looking for
- a confirmed diagnosis of idiopathic Parkinson's disease
- absence of freezing of gait confirmed by a "No" answer to the second item of the New Freezing of Gait Questionnaire (NFOGQ) and no observation of FOG during a freezing provoking test
- no other neurological diagnosis
- no severe musculoskeletal/orthopedic or vestibular condition that interferes with walking and or significantly affects balance
- no mild cognitive impairment (Montreal Cognitive Assessment ≥ 25)
- able to walk independently and without assistive device for 30 minutes
- no previous experience with split-belt treadmill.
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| McGill University - Currie Gymnasium Coordinator of this site? Confirm its status | Montreal | Canada | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.