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NCT07352696Enrolling by invitation

Combined High-Intensity Aerobic Training and Resistance Training in Psoriatic Arthritis

Effects of Combined High-Intensity Aerobic Training and Resistance Training on Cardiovascular and Metabolic Health in Psoriatic Arthritis

Source: ClinicalTrials.gov · Last updated 23 Oct 2026

Brief summary (registry, in English)

The goal of this randomised controlled trial is to evaluate the effects of a 12-week intervention comprising high-intensity interval aerobic training and strength training on cardiovascular function, metabolic health profile and inflammation in patients with Psoriatic arthritis. A secondary goal is to assess the intervention´s impact on physical fitness, pain, fatigue, and health-related quality of life, and to explore long-term maintenance of exercise following completion of the intervention. We hypothesize that 12 weeks of combined high-intensity interval aerobic training and strength training will improve cardiometabolic health, inflammation, and enhance physical fitness, fatigue, pain and quality of life in Psoriatic arthritis.

Status (registry)
Enrolling by invitation
Study type
Interventional
Enrollment
88 (estimated)
First submitted
15 Dec 2025
Start date
26 Jan 2026
Primary completion date
Dec 2027
Lead sponsor
Vastra Gotaland Region
NCT number
NCT07352696

What you commit to

  • Study type: Interventional
  • Planned participants: 88
  • From 26 Jan 2026 to the primary completion date, Dec 2027
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study design.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Ongoing or planned initiation (within 3 months) of structured weight reduction therapy, pharmacological obesity treatment, or bariatric bypass surgery

Other illness

  • Cardiovascular disease
  • Severe hypertension
  • Diabetes type I
  • Chronic obstructive pulmonary disease or other severe pulmonary diseases
  • Severe functional impairment precluding participation in high-intensity aerobic exercise

Other

  • Arthroplasty of large joints, lower extremities
  • Inability to perform a cardiopulmonary exercise testing (CPET)
  • Pregnancy
  • BMI ≥35 kg/m²
  • Already participating in regular exercise at high intensity (BORG ≥15) for \>1 hour/ week during the past 6 months
  • Inability to understand and read Swedish

Who the study is looking for

  • Psoriatic arthritis disease according to the CASPAR (Classification Criteria for Psoriatic Arthritis) criteria
  • Age range 18-65 years
  • Stable medication on anti- rheumatic drugs for \>3 months prior to inclusion and throughout the first 3 months of the study

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
Sahlgrenska University Hospital
Coordinator of this site? Confirm its status
GothenburgSwedenUnknown status
Skaraborgs sjukvård, Skövde
Coordinator of this site? Confirm its status
SkövdeSwedenUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.