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NCT07353879Completed

Application of Cerebellar tDCS in Aphasia

Exploring the Effects of a Computerized Naming Intervention Combined With Cerebellar tDCS in Cantonese-Speaking Individuals With Aphasia

Source: ClinicalTrials.gov · Last updated 21 Jan 2026

Brief summary (registry, in English)

The goal of this clinical trial is to learn if adding brain stimulation (cerebellar anodal tDCS) helps a computer-based therapy improve word-finding in Cantonese-speaking adults with aphasia after stroke. It will also check if the stimulation is safe and comfortable. The main questions it aims to answer are: Does real brain stimulation during therapy help people name pictures (both objects and actions) better and faster than fake (sham) stimulation? Are there different effects on naming nouns (objects) versus verbs (actions)? Do any participants feel side effects like tingling or discomfort from the stimulation? Researchers will compare real brain stimulation to sham (fake) stimulation while everyone gets the same 5-day computer therapy. Participants will: Do 60 minutes of computer word-naming practice every day for 5 days, twice (once with real stimulation, once with sham), with at least 2 weeks break in between Wear a cap with electrodes on the back of the head for the first 20 minutes of each session to receive either real or sham brain stimulation Name pictures on a computer before and after each 5-day block to measure improvement Report any feelings or side effects after each session

Status (registry)
Completed
Study type
Interventional
Enrollment
6 (actual)
First submitted
29 Dec 2025
Start date
3 Jan 2024
Primary completion date
15 Apr 2024
Lead sponsor
The University of Hong Kong
Diseases
Stroke
NCT number
NCT07353879

What you commit to

  • Study type: Interventional
  • Participants enrolled: 6
  • From 3 Jan 2024 to the primary completion date, 15 Apr 2024
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Prior neurological treatment (other than stroke-related)

Other illness

  • History of brain surgery
  • Seizures within past 12 months
  • Conditions contraindicated for tDCS (e.g., metallic implants, pacemakers)
  • Severe cognitive impairment

Other

  • Naming accuracy \<10% or \>80% on noun/verb naming screening pretestt.

Who the study is looking for

  • Native Cantonese speakers
  • Age: 40-80 years
  • Diagnosed with aphasia
  • Single left-hemispheric stroke ≥6 months prior
  • Premorbid right-handedness
  • Normal or corrected-to-normal vision
  • Functional hearing (with or without hearing aids)

Age in the registry: 40 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
The University of Hong Kong
Coordinator of this site? Confirm its status
Hong KongHong Kong SAR ChinaUnknown status
Speech and Neuromodulation Lab
Coordinator of this site? Confirm its status
Hong KongHong Kong SAR ChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.