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NCT07353918Enrolling by invitation

Low-Intensity Focused Ultrasound Neuromodulation for Epilepsy

Neuromodulation Using Low-intensity Focused Ultrasound for Potential Treatment for Medically Refractory Temporal Lobe Epilepsy

Source: ClinicalTrials.gov · Last updated 21 Jan 2026

Brief summary (registry, in English)

This study is an invite only study looking at the effects of Low-Intensity Focused Ultrasound (LIFU) on epilepsy patients with implanted electrodes under the care of Dr. Shah.

Status (registry)
Enrolling by invitation
Study type
Interventional
Enrollment
6 (estimated)
First submitted
22 Dec 2025
Start date
13 Oct 2025
Primary completion date
Dec 2027
Lead sponsor
Carilion Clinic
Diseases
Epilepsy
NCT number
NCT07353918

What you commit to

  • Study type: Interventional
  • Planned participants: 6
  • From 13 Oct 2025 to the primary completion date, Dec 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • TBI (ongoing, or in the prior 6 months)

Other illness

  • Progressive diseases - such as autoimmune epilepsies or diagnosis of a progressive neurological disorder
  • History of suicidal ideation or attempts in the last 6 months

Other

  • Currently pregnant or breastfeeding
  • Status epilepticus within one year of study start

Who the study is looking for

  • Diagnosis of medically refractory focal epilepsy of mesial temporal onset
  • RNS system implantation in the hippocampus
  • Prior MRI and CT of the head
  • Able to consent for themselves
  • Internet access

Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Fralin Biomedical Research Institute at VTC
Coordinator of this site? Confirm its status
RoanokeUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.