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NCT07354282Completed

Real World Evidence of Tivozanib as First-line Treatment for Metastatic Clear Cell Renal Cell Carcinoma

Retrospective, Multicenter, Real-world Observational Study of Tivozanib as First-line Treatment for Metastatic Clear Cell Renal Cell Carcinoma.

Source: ClinicalTrials.gov · Last updated 21 Jan 2026

Brief summary (registry, in English)

The SOGUG-TIVOREAL study is a retrospective observational study with medications. This study is based on the retrospective collection of data from patients who have been treated with Tivozanib as first-line therapy between 03/01/2019 and 08/31/2024 for metastatic renal cell carcinoma (mRCC).

Status (registry)
Completed
Study type
Observational
Enrollment
200 (actual)
First submitted
24 Sept 2025
Start date
May 2025
Primary completion date
Aug 2025
Lead sponsor
Spanish Oncology Genito-Urinary Group
NCT number
NCT07354282

What you commit to

  • Study type: Observational
  • Participants enrolled: 200
  • From May 2025 to the primary completion date, Aug 2025
  • 14 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • \- Patients previously treated at another center who were later referred to one of the participating centers. In this case, the patient will be included in the center where the treatment was initiated.

Other

  • \- Explicit objection by the subject or their legal representative to participate in the study.

Who the study is looking for

  • \- Patients ≥ 18 years old.
  • \- Who have signed the informed consent form, except for patients who were deceased at the time of inclusion.
  • \- Histological diagnosis of stage IV clear cell renal carcinoma.
  • \- Who started treatment with Tivozanib as first-line therapy between March 1, 2019, and August 31, 2024.
  • \- Who received treatment at the participating center.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (14)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Hospital Vall de Hebron
Coordinator of this site? Confirm its status
BarcelonaSpainUnknown status
Hospital de Burgos
Coordinator of this site? Confirm its status
BurgosSpainUnknown status
Hospital Reina Sofia
Coordinator of this site? Confirm its status
CórdobaSpainUnknown status
Hospital Severo Ochoa
Coordinator of this site? Confirm its status
LeganésSpainUnknown status
Hospital de León
Coordinator of this site? Confirm its status
LeónSpainUnknown status
Institut Català d'Oncologia (ICO) de L'Hospitalet de Llobregat
Coordinator of this site? Confirm its status
L'Hospitalet de LlobregatSpainUnknown status
Hospital Lucus Augusti
Coordinator of this site? Confirm its status
LugoSpainUnknown status
Hospital Gregorio Marañon
Coordinator of this site? Confirm its status
MadridSpainUnknown status
Fundación Jiménez Díaz
Coordinator of this site? Confirm its status
MadridSpainUnknown status
Hospital Puerta de Hierro
Coordinator of this site? Confirm its status
MajadahondaSpainUnknown status
Hospital Virgen de la Victoria
Coordinator of this site? Confirm its status
MálagaSpainUnknown status
Hospital Parc Tauli
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SabadellSpainUnknown status
Hospital Virgen Del Rocio
Coordinator of this site? Confirm its status
SevilleSpainUnknown status
Instituto Valenciano de Oncología (IVO)
Coordinator of this site? Confirm its status
ValenciaSpainUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.