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NCT07354399Recruiting

Resistance Training Added to Aerobic Interval Training to Improve Aerobic Capacity and Muscle Mass in Women With Coronary Artery Disease

Resistance Training Among Women With Coronary Artery Disease

Source: ClinicalTrials.gov · Last updated 21 Jan 2026

Brief summary (registry, in English)

The goal of this clinical trial is to find out whether partly replacing aerobic interval training (AIT) with resistance training (RT) leads to greater improvements in physical fitness and muscle mass in women with coronary artery disease (CAD) during cardiac rehabilitation. The main questions this study aims to answer are: * Does combining RT (squats and pulling exercises with weights) with a reduced amount of AIT (cycling) improve aerobic fitness in the same way as AIT alone? * Does the combined training lead to greater improvements in muscle mass compared with AIT alone? * Does slow-speed RT (slower lowering phase) result in lower heart rate and blood pressure during exercise compared with normal-speed RT? Researchers will compare three exercise programs: * AIT only (control group), * AIT combined with normal-speed RT (1-second lifting, 2-second lowering), * AIT combined with slow-speed RT (1-second lifting, 5-second lowering). Participants will take part in a 12-week cardiac rehabilitation program and will train three times per week. At the start and end of the program, participants will complete a cycling fitness test, body composition assessment, blood sampling, two strength tests, and quality-of-life questionnaire.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
50 (estimated)
First submitted
8 Dec 2025
Start date
26 Sept 2025
Primary completion date
Oct 2026
Lead sponsor
University Medical Centre Ljubljana
NCT number
NCT07354399

What you commit to

  • Study type: Interventional
  • Planned participants: 50
  • From 26 Sept 2025 to the primary completion date, Oct 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • based on the American Heart Association guidelines for resistance training in patients with CAD,

Other

  • pregnancy.

Who the study is looking for

  • documented CAD,
  • stable clinical status (at least 1 month since myocardial infarction and/or elective percutaneous coronary intervention, at least 3 months since cardiac surgery).

Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University Medical Centre Ljubljana (Department of Vascular Diseases, Division of Internal Medicine)
Coordinator of this site? Confirm its status
LjubljanaSloveniaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.