NCT07357155Not yet recruiting
Oral and Salivary Biomarkers Associated With Stroke
An Observational Study of Oral and Salivary Biomarkers Associated With Stroke
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
This observational study aims to investigate associations between oral and salivary biomarkers and stroke. Adults with stroke and healthy controls will undergo clinical oral assessment and unstimulated saliva collection. Salivary inflammatory biomarkers and oral bacterial profiles will be analyzed, including detection of Streptococcus mutans and the cnm gene by PCR/qPCR. The study will explore associations between these biomarkers and stroke status.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 120 (estimated)
- First submitted
- 13 Jan 2026
- Start date
- 20 Dec 2026
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- University Hospital Center (CHU) of Constantine, Algeria
- Diseases
- Stroke
- NCT number
- NCT07357155
What you commit to
- Study type: Observational
- Planned participants: 120
- From 20 Dec 2026 to the primary completion date, 30 Jun 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent major surgery or trauma within the last 3 months.
Other illness
- inflammatory disease at the time of sampling.
- Chronic autoimmune or malignant disease.
Other
- Pregnancy or breastfeeding.
- Inability or refusal to provide saliva samples.
Who the study is looking for
- Adults aged 18 to 90 years.
- Patients diagnosed with stroke (ischemic or hemorrhagic) confirmed by clinical and imaging criteria for the stroke group.
- Healthy volunteers without a history of stroke or cerebrovascular disease for the control group.
- Ability to provide written informed consent.
Age in the registry: 18 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Center (CHU) of Constantine Coordinator of this site? Confirm its status | Constantine | Algeria | Unknown status |
| Private Dental Clinic, Constantine Coordinator of this site? Confirm its status | Constantine | Algeria | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.