NCT07358429Active, not recruiting
CPAP Therapy and Atrial Fibrillation Recurrence in OSA
Effects of CPAP Therapy on Atrial Fibrillation Recurrence in Patients With Obstructive Sleep Apnea: A Prospective Cohort Study
Source: ClinicalTrials.gov · Last updated 22 Jan 2026
Brief summary (registry, in English)
Obstructive sleep apnea (OSA) is a major modifiable risk factor for atrial fibrillation (AF). Continuous positive airway pressure (CPAP) therapy has been shown to improve cardiovascular outcomes; however, real-world data on its effect on AF recurrence remain limited. This prospective cohort study aims to evaluate the association between objective CPAP adherence and the risk of AF recurrence in patients with moderate-to-severe OSA and a history of paroxysmal AF. Patients will be followed for 12 months, with AF recurrence assessed using electrocardiography and Holter monitoring.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 91 (actual)
- First submitted
- 14 Jan 2026
- Start date
- 1 Sept 2024
- Primary completion date
- 30 Nov 2025
- Lead sponsor
- Medical University of Sofia
- Diseases
- Atrial fibrillation
- NCT number
- NCT07358429
What you commit to
- Study type: Observational
- Participants enrolled: 91
- From 1 Sept 2024 to the primary completion date, 30 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Inability to obtain or tolerate CPAP therapy -
Other illness
- End-stage chronic kidney disease
Lab values
- Left ventricular ejection fraction \< 50%
Other
- Permanent atrial fibrillation
- Central sleep apnea
Who the study is looking for
- Age ≥ 18 years
- Diagnosed moderate-to-severe OSA
- History of paroxysmal atrial fibrillation
- Ability to initiate CPAP therapy
- Written informed consent -
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UMHAT "Tcaritca Joanna - ISUL" Coordinator of this site? Confirm its status | Sofia | Bulgaria | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.