NCT07358572Recruiting
Eye-Brain-Kidney in CKD
A Study on the Eye-Brain-Kidney Interaction Mechanisms in Chronic Kidney Disease Based on Multimodal Magnetic Resonance Imaging
Source: ClinicalTrials.gov · Last updated 27 Jan 2026
Brief summary (registry, in English)
The goal of this observational study is to learn about the interaction between the eyes, brain, and kidneys in adult patients with Chronic Kidney Disease (CKD). The main question it aims to answer is: Do changes in the brain's network connectivity and the retina's blood vessels correlate with cognitive decline and kidney function in CKD patients? Participants with CKD who are already undergoing clinical care will complete cognitive tests and questionnaires, have non-invasive MRI scans of their brain and kidneys, and undergo non-invasive eye imaging (OCT/OCTA) of their retinas.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1500 (estimated)
- First submitted
- 26 Dec 2025
- Start date
- 1 Dec 2025
- Primary completion date
- 31 Dec 2031
- Lead sponsor
- Beijing Friendship Hospital
- Diseases
- Chronic kidney disease
- NCT number
- NCT07358572
What you commit to
- Study type: Observational
- Planned participants: 1500
- From 1 Dec 2025 to the primary completion date, 31 Dec 2031
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with recent or prior cerebral hemorrhage or cerebral infarction.
Other illness
- History of epileptic seizures or psychiatric disorders.
- Presence of other central nervous system diseases (e.g., tumor, trauma).
- Unstable angina, congestive heart failure (NYHA class III or IV), or acute myocardial infarction.
- Any systemic or other diseases deemed unsuitable for clinical trial participation.
Other
- Patients with claustrophobia.
- Pregnant or lactating patients.
Who the study is looking for
- Aged 18-70 years.
- Patients clinically diagnosed with CKD stages 1-5.
- No contraindications for MRI examination (e.g., cardiac pacemaker, claustrophobia, cochlear implant, hearing aid, coronary stents implanted before 2015) and able to complete the MRI scan.
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Beijing Friendship Hospital, Capital Medical University Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.