NCT07359664Recruiting
OCTA in Cardiovascular Disease and Healthy Controls
Optical Coherence Tomography Angiography (OCTA) for the Assessment of Retinal Capillary Density in Patients With Cardiovascular Disease and a Healthy Control Group
Source: ClinicalTrials.gov · Last updated 22 Jan 2026
Brief summary (registry, in English)
This prospective clinical study will involve the non-invasive assessment of retinal vessels using OCTA (Cirrus OCT 6000 AngioPlex) and scanning laser Doppler flowmetry (SLDF) in patients with cardiovascular disease and healthy individuals. The study will be conducted at the Clinical Research Centre (CRC), Department of Nephrology and Hypertension at the University of Erlangen-Nuremberg.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 64 (estimated)
- First submitted
- 9 Dec 2025
- Start date
- 1 Dec 2025
- Primary completion date
- Dec 2026
- Lead sponsor
- University of Erlangen-Nürnberg Medical School
- NCT number
- NCT07359664
What you commit to
- Study type: Interventional
- Planned participants: 64
- From 1 Dec 2025 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- a clinically relevant history of cardiovascular disease or any other previously known cardiovascular disease
- regular intake of any medication for the treatment of cardiovascular diseases (e.g. antihypertensive or antidiabetic medication) within one month before study inclusion
- alcohol or drug abuse
Other illness
- Active ophthalmological (retinal) disease resulting in impaired visual assessment of retinal vessels (e.g. glaucoma, cataracts, retinal oedema).
- Active ophthalmological (retinal) disease with reduced visual assessment of retinal vessels (e.g. glaucoma, cataracts, retinal oedema).
- History of clinically relevant neurological, gastrointestinal, renal, hepatic, psychological, pulmonary, metabolic, endocrine or other diseases
- Office heart rate outside of the following range: 50-99 bpm
Lab values
- clinically relevant deviation in physical examination, vital signs, or laboratory parameters (based on the physician's clinical judgement).
Other
- office blood pressure above or equal to 140/90 mmHg
Who the study is looking for
- cardiovascular disease defined as one or more of the following: arterial hypertension, type 2 diabetes mellitus, chronic kidney disease, heart failure
- BMI 18-29.9 kg/m2
- Non-smoker
- Good general health, as determined by study personnel based on assessments of previous visits, including anamnesis, vital signs, physical examination and clinical laboratory parameters.
Age in the registry: 18 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Of Erlangen Nuremberg Coordinator of this site? Confirm its status | Erlangen | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.