Fact CheckerSign in

NCT07360964Active, not recruiting

Clear Cell Chondrosarcoma in Italy

Clear Cell Chondrosarcoma in Italy: Insights Into Radiological, Clinical and pathologicaL Features, With Emphasis on Prognosis (CIRCLE)

Source: ClinicalTrials.gov · Last updated 4 Nov 2026

Brief summary (registry, in English)

Clear cell chondrosarcoma of bone is considered a low-grade malignant tumor in the last WHO classification of soft tissue and bone tumors; however, it is reported that recurrences and metastasis can occur. Considering the uncertain prognosis of this rare tumor, with some cases that historically seems to pursue a bad prognosis, we decided to collect all the Italian cases of clear cell condrosarcoma, in order to better understand its natural history and prognosis.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
77 (actual)
First submitted
8 Jan 2026
Start date
10 Sept 2025
Primary completion date
31 Dec 2025
Lead sponsor
Istituto Ortopedico Rizzoli
Diseases
Sarcoma
NCT number
NCT07360964

What you commit to

  • Study type: Interventional
  • Participants enrolled: 77
  • From 10 Sept 2025 to the primary completion date, 31 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • \- Diagnosis different from clear cell chondrosarcoma or chondrosarcoma with a clear cell component;
  • Absence of radiological and/or clinical data

Who the study is looking for

  • Male and female patients with diagnosis of clear cell chondrosarcoma and chondrosarcoma with a clear cell component treated from 01 Jan 1982 to 31 Dec 2023
  • Information available (date of primary tumor diagnosis, local treatments, systemic treatment, response to systemic treatment, date of progression) and date and status at last follow-up
  • Imaging studies available for revision
  • Histological slides available for revision

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
IRCC Rizzoli Orthopedic Institute
Coordinator of this site? Confirm its status
BolognaItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.