NCT07361146Recruiting
A Comparative Study of Intradialytic vs. Pre-Dialysis Physical Therapy Interventions in Individuals Undergoing Hemodialysis: A Randomized Controlled Trial
A Comparative Study of Intradialytic Versus Pre-Dialysis Physical Therapy Interventions in Individuals Undergoing Hemodialysis: A Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 22 Jan 2026
Brief summary (registry, in English)
This randomized controlled trial aims to compare the effectiveness of two different timings of physical therapy for individuals undergoing hemodialysis: intradialytic (during dialysis) and pre-dialysis (before dialysis). The study seeks to determine which approach provides better improvements in physical function, quality of life, and biochemical outcomes such as hemoglobin and electrolyte levels. A total of 72 adult participants with end-stage renal disease (ESRD) receiving hemodialysis will be randomly assigned to one of two groups. Both groups will receive standardized educational sessions on the benefits and safety of exercise before beginning the intervention. Participants in the intradialytic group will perform supervised exercises during their dialysis sessions, while those in the pre-dialysis group will complete similar exercises before their dialysis sessions. Each participant will undergo the intervention twice per week for 12 weeks. Primary outcomes include physical function, assessed using the Six-Minute Walk Test and the Five Times Sit-to-Stand Test. Secondary outcomes include hemoglobin levels, electrolyte balance, and health-related quality of life measured by the KDQOL questionnaire. The study will be conducted at Mubarak Al-Abdullah Al-Jaber Al-Sabah Dialysis Center, Kuwait, following ethical approval from the Ministry of Health Research Ethics Committee. The results are expected to inform best practices for integrating physical therapy into dialysis care to enhance the health, safety, and well-being of individuals undergoing hemodialysis.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 72 (estimated)
- First submitted
- 6 Jan 2026
- Start date
- 2 Mar 2025
- Primary completion date
- 2 Mar 2027
- Lead sponsor
- Mohammad Arian
- Diseases
- Chronic kidney disease
- NCT number
- NCT07361146
What you commit to
- Study type: Interventional
- Planned participants: 72
- From 2 Mar 2025 to the primary completion date, 2 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Uncontrolled hypertension, recent myocardial infarction, or unstable angina.
- Severe musculoskeletal, neurological, or cardiovascular disorders that limit physical activity.
- Active infection, fever, or open wounds.
Other
- Recent hospitalization within the past month.
- Participation in any other structured exercise program within the last 3 months.
Who the study is looking for
- Adults aged between 21 and 65 years.
- Diagnosed with end-stage renal disease (ESRD).
- Undergoing maintenance hemodialysis for at least 3 months.
- Medically stable and cleared by the nephrologist to participate in moderate physical exercise.
- Able to understand and follow verbal instructions and provide informed consent.
Age in the registry: 21 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mubarak Al-Abdullah Al-Jaber Al-Sabah Dialysis Center Coordinator of this site? Confirm its status | Hawalli | Kuwait | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.