NCT07361887Recruiting
Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles.
Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles
Source: ClinicalTrials.gov · Last updated 23 Jan 2026
Brief summary (registry, in English)
This study aims to investigate how moderate wine consumption influences circulating extracellular vesicles (EVs) in healthy adults. EVs are small particles released by cells that carry proteins, lipids, and genetic material, and play important roles in communication between cells. Participants will consume a single serving of red or white wine, and blood samples will be collected before and after consumption to study changes in the composition and function of EVs. The study will also assess how these EVs affect vascular, immune, and brain-related cells. The results are expected to improve our understanding of how moderate wine intake contributes to cardiovascular and brain health.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 8 (estimated)
- First submitted
- 2 Dec 2025
- Start date
- 1 Nov 2025
- Primary completion date
- 1 Dec 2025
- Lead sponsor
- University of Seville
- Diseases
- Obesity, Alzheimer disease
- NCT number
- NCT07361887
What you commit to
- Study type: Interventional
- Planned participants: 8
- From 1 Nov 2025 to the primary completion date, 1 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participation in another clinical or biomedical study within the previous 3 months.
Other illness
- History or clinical evidence of cardiovascular, hepatic, renal, thyroid, gastrointestinal, or metabolic diseases (including diabetes, dyslipidemia, or hypertension).
- Known allergy or intolerance to wine, alcohol, or its components (e.g., sulfites).
- History of alcohol abuse or inability to abstain from alcohol outside the study context.
- Any condition judged by the investigators to limit compliance or increase study risk (e.g., psychiatric disorders, inability to adhere to fasting requirements).
Lab values
- Use of medications or supplements known to affect glucose, lipid, or inflammatory metabolism (e.g., statins, corticosteroids, anti-inflammatory drugs).
Other
- Pregnancy or breastfeeding.
- Recent blood donation (within the last 3 months) or planned blood donation during the study period.
- Major weight change (\>5% of body weight) within the last 3 months.
- Reluctance to receive information about incidental health findings arising from the study.
Who the study is looking for
- Healthy adult men and women aged 35 to 65 years.
- Body Mass Index (BMI) between 18.5 and 29.9 kg/m².
- Non-smokers or ex-smokers for at least 12 months.
- Moderate alcohol consumers, defined as ≤2 units/day for men and ≤1 unit/day for women.
- Normal fasting glucose and lipid profile at screening.
- Willing and able to refrain from alcohol, polyphenol-rich foods, and intense exercise for 48 hours before each study visit.
- Able to understand the study procedures and provide written informed consent.
Age in the registry: 35 years to 36 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Av. de Sánchez Pizjuán, s/n, 41009 Sevilla Facultad de Medicina . Universidad de Sevilla Coordinator of this site? Confirm its status | Seville | Spain | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.