NCT07362017RecruitingPhase 3
Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque Psoriasis
A Multicenter, Open Label Study to Investigate the Safety and Efficacy of Ponesimod in the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis
Source: ClinicalTrials.gov · Last updated 22 Sept 2026
Brief summary (registry, in English)
An open label study to investigate the safety and efficacy of ponesimod in participants with moderate-to-severe chronic plaque psoriasis
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 300 (estimated)
- First submitted
- 20 Jan 2026
- Start date
- 17 Feb 2026
- Primary completion date
- 31 Aug 2028
- Lead sponsor
- Vanda Pharmaceuticals
- Diseases
- Psoriasis
- NCT number
- NCT07362017
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 300
- From 17 Feb 2026 to the primary completion date, 31 Aug 2028
- 10 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of an allergic reaction or known and/or significant sensitivity to study drug
Other
- Diagnosis of generalized erythrodermic, generalized pustular (von Zumbusch), guttate, or palmoplantar psoriasis
Who the study is looking for
- Male and female subjects aged 18-65 years, inclusive
- BMI \>18 and \<40
- Minimum affected BSA of 10%
- PASI score ≥ 12
- PGA ≥ 3
- Diagnosed with moderate-to-severe plaque psoriasis
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (10)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Vanda Investigational Site Coordinator of this site? Confirm its status | Fremont | United States | Recruiting |
| Vanda Investigational Site Coordinator of this site? Confirm its status | Glendale | United States | Recruiting |
| Vanda Investigational Site Coordinator of this site? Confirm its status | Indianapolis | United States | Recruiting |
| Vanda Investigational Site Coordinator of this site? Confirm its status | Miami | United States | Recruiting |
| Vanda Investigational Site Coordinator of this site? Confirm its status | Portsmouth | United States | Recruiting |
| Vanda Investigational Site Coordinator of this site? Confirm its status | Rochester | United States | Recruiting |
| Vanda Investigational Site Coordinator of this site? Confirm its status | San Antonio | United States | Recruiting |
| Vanda Investigational Site Coordinator of this site? Confirm its status | Spokane | United States | Recruiting |
| Vanda Investigational Site Coordinator of this site? Confirm its status | Webster | United States | Recruiting |
| Vanda Investigational Site Coordinator of this site? Confirm its status | Wilmington | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.