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NCT07362953Completed

Paraclinical Cardiometabolic Risk Assessment in Type 2 Diabetes

Paraclinical Assessment of Cardiometabolic Risk Based on Novel Biochemical İndices in Type 2 Diabetes

Source: ClinicalTrials.gov · Last updated 23 Jan 2026

Brief summary (registry, in English)

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by impaired insulin action and increased cardiometabolic risk. Visceral adiposity, insulin resistance, systemic inflammation, and dyslipidemia play key roles in the development of cardiovascular disease in individuals with T2DM. In this context, simple, rapid, and cost-effective biomarkers are increasingly important for risk assessment. The triglyceride-glucose (TyG) index is a practical indicator of insulin resistance, while the Atherogenic Plasma Index (API) reflects cardiovascular risk related to dyslipidemia. The Systemic Immune Inflammation Index (SII), derived from routine blood counts, serves as a marker of systemic inflammation. This study aims to evaluate the predictive value of TyG, API, and SII in assessing insulin resistance, cardiometabolic risk, and inflammation in patients with T2DM, thereby supporting early diagnosis and improved clinical management.

Status (registry)
Completed
Study type
Observational
Enrollment
2188 (actual)
First submitted
8 Jan 2026
Start date
1 Mar 2025
Primary completion date
15 Nov 2025
Lead sponsor
Tokat Gaziosmanpasa University
NCT number
NCT07362953

What you commit to

  • Study type: Observational
  • Participants enrolled: 2188
  • From 1 Mar 2025 to the primary completion date, 15 Nov 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Receiving hormone therapy

Other illness

  • Having any other chronic disease accompanying T2DM/prediabetes
  • Having an acute infection
  • Having any malignant/inflammatory disease

Other

  • Using lipid-lowering agents
  • Being pregnant/breastfeeding

Who the study is looking for

  • Having a diagnosis of T2DM
  • Having a diagnosis of prediabetes
  • Being between 18 and 65 years of age.

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Tokat Gaziosmanpaşa University Health Research and Application Hospital
Coordinator of this site? Confirm its status
Tokat ProvinceTurkey (Türkiye)Unknown status

This page is information, not medical advice. Discuss any trial with your doctor.