NCT07363980Enrolling by invitation
Coronary Computed Tomography Angiography In Rheumatoid Arthritis Study
Source: ClinicalTrials.gov · Last updated 3 Feb 2026
Brief summary (registry, in English)
The Coronary Computed Tomography Angiography in Rheumatoid Arthritis study is part of the multinational, prospective, observational Autoimmunity and Atherosclerosis in Rheumatic Diseases cohort (https://atacc-rd.com) that includes comprehensive baseline and follow-up assessments at 3, 5, and 10 years. It comprises a main protocol and several optional modules, including a Cardiac Imaging Module, Biobanking Module, Pulmonary Module, and Anxiety and Depression Module. The study aims to advance understanding of cardiopulmonary and psychological comorbidities in rheumatoid arthritis, to improve early identification and management, and to enhance insights into underlying disease mechanisms-ultimately refining risk stratification and targeted prevention strategies. The study includes 4,000 patients with rheumatoid arthritis enrolled through the Cardiac Imaging Module in the main protocol. Participants undergo coronary computed tomography angiography, pulmonary function testing, physical examination, questionnaires, and biobanking, supplemented by genetic, proteomic, metabolomic, and microbiome profiling.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 4000 (estimated)
- First submitted
- 15 Jan 2026
- Start date
- 21 Feb 2024
- Primary completion date
- 31 Dec 2038
- Lead sponsor
- Ellen Margrethe Hauge
- Diseases
- Rheumatoid arthritis, COPD, Lung cancer
- NCT number
- NCT07363980
What you commit to
- Study type: Observational
- Planned participants: 4000
- From 21 Feb 2024 to the primary completion date, 31 Dec 2038
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior coronary atherosclerotic symptoms as defined by myocardial infraction, percutaneous coronary intervention, or coronary artery bypass grafting
Other illness
- Diagnosed with overlapping systemic autoimmune diseases other than secondary Sjogren's syndrome
- Active cancer
- Allergy to radiocontrast agents
Lab values
- Estimated glomerular filtration rate (eGFR) \< 30 mL/min
Other
- BMI \> 35 kg/m2
- Persistent atrial fibrillation
Who the study is looking for
- Fulfill the ACR/EULAR-2010 criteria for rheumatoid arthritis
- Attending or has attended at least one visit during the last two years in rheumatology outpatient clinic for diagnostic or monitoring purposes related to rheumatoid arthritis
- Age 50-75 years
Age in the registry: 50 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aarhus University Hospital Coordinator of this site? Confirm its status | Aarhus | Denmark | Unknown status |
| Esbjerg Hospital Coordinator of this site? Confirm its status | Esbjerg | Denmark | Unknown status |
| Regional Hospital Gødstrup Coordinator of this site? Confirm its status | Herning | Denmark | Unknown status |
| Silkeborg Regional Hospital Coordinator of this site? Confirm its status | Herning | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.